8g26

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m (Protected "8g26" [edit=sysop:move=sysop])
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'''Unreleased structure'''
 
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The entry 8g26 is ON HOLD until Paper Publication
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==Crystal Structure of Cathepsin-G and Neutrophil Elastase Inhibited by S. aureus EapH2 at pH 8.5==
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<StructureSection load='8g26' size='340' side='right'caption='[[8g26]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
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Authors: Mishra, N.B., Geisbrecht, B.V.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8g26]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_Mu50 Staphylococcus aureus subsp. aureus Mu50]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8G26 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8G26 FirstGlance]. <br>
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Description: Crystal Structure of Cathepsin-G and Neutrophil Elastase Inhibited by S. aureus EapH2 at pH 8.5
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8g26 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8g26 OCA], [https://pdbe.org/8g26 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8g26 RCSB], [https://www.ebi.ac.uk/pdbsum/8g26 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8g26 ProSAT]</span></td></tr>
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[[Category: Geisbrecht, B.V]]
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</table>
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[[Category: Mishra, N.B]]
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== Function ==
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[https://www.uniprot.org/uniprot/CATG_HUMAN CATG_HUMAN] Serine protease with trypsin- and chymotrypsin-like specificity. Cleaves complement C3. Has antibacterial activity against the Gram-negative bacterium P.aeruginosa, antibacterial activity is inhibited by LPS from P.aeruginosa, Z-Gly-Leu-Phe-CH2Cl and phenylmethylsulfonyl fluoride.<ref>PMID:8194606</ref> <ref>PMID:1861080</ref> <ref>PMID:1937776</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Staphylococcus aureus subsp. aureus Mu50]]
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[[Category: Geisbrecht BV]]
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[[Category: Mishra NB]]

Revision as of 17:07, 26 April 2023

Crystal Structure of Cathepsin-G and Neutrophil Elastase Inhibited by S. aureus EapH2 at pH 8.5

PDB ID 8g26

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