1jxa

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1jxa.gif|left|200px]]
+
{{Seed}}
 +
[[Image:1jxa.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1jxa| PDB=1jxa | SCENE= }}
{{STRUCTURE_1jxa| PDB=1jxa | SCENE= }}
-
'''GLUCOSAMINE 6-PHOSPHATE SYNTHASE WITH GLUCOSE 6-PHOSPHATE'''
+
===GLUCOSAMINE 6-PHOSPHATE SYNTHASE WITH GLUCOSE 6-PHOSPHATE===
-
==Overview==
+
<!--
-
Glucosamine-6-phosphate synthase catalyses the first and rate-limiting step in hexosamine metabolism, converting fructose 6-phosphate into glucosamine 6-phosphate in the presence of glutamine. The crystal structure of the Escherichia coli enzyme reveals the domain organisation of the homodimeric molecule. The 18 A hydrophobic channel sequestered from the solvent connects the glutaminase and isomerase active sites, and provides a means of ammonia transfer from glutamine to sugar phosphate. The C-terminal decapeptide sandwiched between the two domains plays a central role in the transfer. Based on the structure, a mechanism of enzyme action and self-regulation is proposed. It involves large domain movements triggered by substrate binding that lead to the formation of the channel.
+
The line below this paragraph, {{ABSTRACT_PUBMED_11700065}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 11700065 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_11700065}}
==About this Structure==
==About this Structure==
Line 30: Line 34:
[[Category: Gene duplication]]
[[Category: Gene duplication]]
[[Category: Nucleotide-binding fold]]
[[Category: Nucleotide-binding fold]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 22:02:11 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 08:24:25 2008''

Revision as of 05:24, 29 July 2008

Image:1jxa.png

Template:STRUCTURE 1jxa

GLUCOSAMINE 6-PHOSPHATE SYNTHASE WITH GLUCOSE 6-PHOSPHATE

Template:ABSTRACT PUBMED 11700065

About this Structure

1JXA is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

Channeling of ammonia in glucosamine-6-phosphate synthase., Teplyakov A, Obmolova G, Badet B, Badet-Denisot MA, J Mol Biol. 2001 Nov 9;313(5):1093-102. PMID:11700065

Page seeded by OCA on Tue Jul 29 08:24:25 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1jxa"
Personal tools