8cks

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m (Protected "8cks" [edit=sysop:move=sysop])
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'''Unreleased structure'''
 
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The entry 8cks is ON HOLD
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==Crystal structure of Human Serum Albumin in complex with FESAN==
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<StructureSection load='8cks' size='340' side='right'caption='[[8cks]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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Authors: Dolot, R.M., Kaniowski, D., Ebenryter-Olbinska, K., Szczupak, P., Suwara, J., Nawrot, B.C.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8cks]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8CKS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8CKS FirstGlance]. <br>
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Description: Crystal structure of Human Serum Albumin in complex with FESAN
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MYR:MYRISTIC+ACID'>MYR</scene>, <scene name='pdbligand=OCA:OCTANOIC+ACID+(CAPRYLIC+ACID)'>OCA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UZC:3,3-commo-bis(1,2-dicarba-3-ferra-closo-dodecaborane)'>UZC</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8cks FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8cks OCA], [https://pdbe.org/8cks PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8cks RCSB], [https://www.ebi.ac.uk/pdbsum/8cks PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8cks ProSAT]</span></td></tr>
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[[Category: Nawrot, B.C]]
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</table>
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[[Category: Kaniowski, D]]
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== Disease ==
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[[Category: Szczupak, P]]
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[https://www.uniprot.org/uniprot/ALBU_HUMAN ALBU_HUMAN] Defects in ALB are a cause of familial dysalbuminemic hyperthyroxinemia (FDH) [MIM:[https://omim.org/entry/103600 103600]. FDH is a form of euthyroid hyperthyroxinemia that is due to increased affinity of ALB for T(4). It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population.<ref>PMID:8048949</ref> <ref>PMID:7852505</ref> <ref>PMID:9329347</ref> <ref>PMID:9589637</ref>
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[[Category: Suwara, J]]
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== Function ==
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[[Category: Dolot, R.M]]
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[https://www.uniprot.org/uniprot/ALBU_HUMAN ALBU_HUMAN] Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.<ref>PMID:19021548</ref>
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[[Category: Ebenryter-Olbinska, K]]
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Dolot RM]]
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[[Category: Ebenryter-Olbinska K]]
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[[Category: Kaniowski D]]
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[[Category: Nawrot BC]]
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[[Category: Suwara J]]
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[[Category: Szczupak P]]

Revision as of 06:03, 2 March 2023

Crystal structure of Human Serum Albumin in complex with FESAN

PDB ID 8cks

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OCA

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