8hxq

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'''Unreleased structure'''
 
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The entry 8hxq is ON HOLD until Paper Publication
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==Nanobody1 in complex with human BCMA ECD==
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<StructureSection load='8hxq' size='340' side='right'caption='[[8hxq]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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Authors: Sun, Y., Zhang, B.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8hxq]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Vicugna_pacos Vicugna pacos]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8HXQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8HXQ FirstGlance]. <br>
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Description: Nanobody1 in complex with human BCMA ECD
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8hxq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8hxq OCA], [https://pdbe.org/8hxq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8hxq RCSB], [https://www.ebi.ac.uk/pdbsum/8hxq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8hxq ProSAT]</span></td></tr>
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[[Category: Zhang, B]]
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</table>
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[[Category: Sun, Y]]
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== Disease ==
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[https://www.uniprot.org/uniprot/TNR17_HUMAN TNR17_HUMAN] Note=A chromosomal aberration involving TNFRSF17 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with IL2.
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== Function ==
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[https://www.uniprot.org/uniprot/TNR17_HUMAN TNR17_HUMAN] Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK.<ref>PMID:10903733</ref> <ref>PMID:10801128</ref> <ref>PMID:10973284</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Vicugna pacos]]
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[[Category: Sun Y]]
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[[Category: Zhang B]]

Revision as of 11:02, 3 January 2024

Nanobody1 in complex with human BCMA ECD

PDB ID 8hxq

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