2m7b
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2m7b]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_putida_KT2440 Pseudomonas putida KT2440]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M7B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2M7B FirstGlance]. <br> | <table><tr><td colspan='2'>[[2m7b]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_putida_KT2440 Pseudomonas putida KT2440]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M7B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2M7B FirstGlance]. <br> | ||
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2m7b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2m7b OCA], [https://pdbe.org/2m7b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2m7b RCSB], [https://www.ebi.ac.uk/pdbsum/2m7b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2m7b ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2m7b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2m7b OCA], [https://pdbe.org/2m7b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2m7b RCSB], [https://www.ebi.ac.uk/pdbsum/2m7b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2m7b ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/Q88G17_PSEPK Q88G17_PSEPK] | [https://www.uniprot.org/uniprot/Q88G17_PSEPK Q88G17_PSEPK] | ||
| - | <div style="background-color:#fffaf0;"> | ||
| - | == Publication Abstract from PubMed == | ||
| - | A cluster of genes in the exoxis region of bacteriophage lambda are capable of inhibiting the initiation of DNA synthesis in Escherichia coli. The most indispensible gene in this region is ea8.5. Here, we report the nuclear magnetic resonance structures of two ea8.5 orthologs from enteropathogenic E. coli and Pseudomonas putida prophages. Both proteins are characterized by a fused homeodomain/zinc-finger fold that escaped detection by primary sequence search methods. While these folds are both associated with a nucleic acid binding function, the amino acid composition suggests otherwise, leading to the possibility that Ea8.5 associates with other viral and host proteins. | ||
| - | |||
| - | The Solution Structures of Two Prophage Homologues of the Bacteriophage lambda Ea8.5 Protein Reveal a Newly Discovered Hybrid Homeodomain/Zinc-Finger Fold.,Kwan JJ, Smirnova E, Khazai S, Evanics F, Maxwell KL, Donaldson LW Biochemistry. 2013 May 14. PMID:23672713<ref>PMID:23672713</ref> | ||
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| - | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
| - | </div> | ||
| - | <div class="pdbe-citations 2m7b" style="background-color:#fffaf0;"></div> | ||
| - | == References == | ||
| - | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Current revision
ORF PP_3909 from Pseudomonas putida KT2440 encoding a protein similar to bacteriophage lambda ea8.5
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