Epidermal growth factor receptor 3D structures
From Proteopedia
(Difference between revisions)
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**[[5wb8]] – hEGFR + epigen<br /> | **[[5wb8]] – hEGFR + epigen<br /> | ||
**[[5wb7]], [[7len]], [[7lfr]], [[7lfs]] – hEGFR + epiregulin<br /> | **[[5wb7]], [[7len]], [[7lfr]], [[7lfs]] – hEGFR + epiregulin<br /> | ||
| + | **[[8hgp]] – hEGFR + HER2 + epiregulin – Cryo EM<br /> | ||
| + | **[[8hgo]] – hEGFR + HER2 + EGF – Cryo EM<br /> | ||
**[[3u7u]] – hEGFR + neuregulin<br /> | **[[3u7u]] – hEGFR + neuregulin<br /> | ||
**[[4krl]], [[4krm]] – EGFR + nanobody – llama<br /> | **[[4krl]], [[4krm]] – EGFR + nanobody – llama<br /> | ||
**[[3i2t]] - DmEGFR – ''Drosophila melanogaster''<br /> | **[[3i2t]] - DmEGFR – ''Drosophila melanogaster''<br /> | ||
**[[3ltf]], [[3ltg]] – DmEGFR + spitz protein <br /> | **[[3ltf]], [[3ltg]] – DmEGFR + spitz protein <br /> | ||
| + | |||
| + | *EGFR residues 298-642 | ||
| + | |||
| + | **[[8ukw]], [[8ukx]] – hEGFR <br /> | ||
| + | **[[8ukv]] – hEGFR + nanobody <br /> | ||
*EGFR residues 335-538 | *EGFR residues 335-538 | ||
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**[[2gs6]] - hERBB1 +peptide<br /> | **[[2gs6]] - hERBB1 +peptide<br /> | ||
**[[5czh]], [[5czi]] - hERBB1 (mutant) +peptide<br /> | **[[5czh]], [[5czi]] - hERBB1 (mutant) +peptide<br /> | ||
| - | **[[5cno]], [[4zse]] - hERBB1 (mutant) + ANP<br /> | + | **[[5cno]], [[4zse]], [[8dsw]] - hERBB1 (mutant) + ANP<br /> |
**[[2gs7]] - hERBB1 +AMPPNP<br /> | **[[2gs7]] - hERBB1 +AMPPNP<br /> | ||
**[[2eb3]], [[2itn]], [[2itv]], [[2itx]], [[3vjn]], [[3vjo]] - hERBB1 (mutant)+AMPPNP<br /> | **[[2eb3]], [[2itn]], [[2itv]], [[2itx]], [[3vjn]], [[3vjo]] - hERBB1 (mutant)+AMPPNP<br /> | ||
**[[2eb2]], [[2jit]], [[1m14]], [[4i1z]], [[4i20]], [[3ug1]] – hERBB1 (mutant)<br /> | **[[2eb2]], [[2jit]], [[1m14]], [[4i1z]], [[4i20]], [[3ug1]] – hERBB1 (mutant)<br /> | ||
| - | **[[2rf9]], [[2rfd]], [[2rfe]], [[1xkk]], [[3lzb]], [[3poz]], [[3w32]], [[3w33]], [[3w2s]], [[4jq7]], [[4jq8]], [[4jr3]], [[4jrv]], [[4li5]], [[4lrm]], [[4r5s]], [[5ug8]], [[5ugb]], [[5em8]], [[5fed]], [[5cav]], [[4zau]], [[6p8q]], [[6vh4]], [[6vhn]], [[6vhp]], [[7b85]], [[7kxz]], [[7u99]], [[7u9a]] - hERBB1 + inhibitor<br /> | + | **[[2rf9]], [[2rfd]], [[2rfe]], [[1xkk]], [[3lzb]], [[3poz]], [[3w32]], [[3w33]], [[3w2s]], [[4jq7]], [[4jq8]], [[4jr3]], [[4jrv]], [[4li5]], [[4lrm]], [[4r5s]], [[5ug8]], [[5ugb]], [[5em8]], [[5fed]], [[5cav]], [[4zau]], [[6p8q]], [[6vh4]], [[6vhn]], [[6vhp]], [[7b85]], [[7kxz]], [[7u99]], [[7u9a]], [[8a27]], [[8d76]], [[8f1z]], [[8hva]], [[8pnz]], [[8sc7]], [[8tjl]], [[9frd]], [[9gdv]], [[9gi9]], [[9gl9]] - hERBB1 + inhibitor<br /> |
| - | **[[2jiu]], [[2jiv]], [[2ito]], [[2itp]], [[2itq]], [[2itt]], [[2itu]], [[2itw]], [[2itz]], [[2j6m]], [[2j5e]], [[2j5f]], [[1m17]], [[3w2o]], [[3w2p]], [[3w2q]], [[3w2r]], [[3w2s]], [[4ll0]], [[4lqm]], [[4rj4]], [[4rj5]], [[4rj6]], [[4rj7]], [[4rj8]], [[5ug9]], [[5uga]], [[5ugc]], [[5em5]], [[5em6]], [[5em7]], [[5fee]], [[5feq]], [[5gnk]], [[5hcx]], [[5hcy]], [[5hcz]], [[5hg5]], [[5hg7]], [[5hg8]], [[5hg9]], [[5hib]], [[5hic]], [[5j9y]], [[5j9z]], [[5jeb]], [[5d41]], [[5edp]], [[5edq]], [[5edr]], [[5c8k]], [[5c8m]], [[5c8n]], [[5cal]], [[5can]], [[5cao]], [[5cap]], [[5caq]], [[5cas]], [[5cau]], [[5cnn]], [[4wd5]], [[5xgm]], [[5xgn]], [[5xdk]], [[5xdl]], [[5x26]], [[5x27]], [[5x28]], [[5x2c]], [[5x2f]], [[5x2k]], [[5uwd]], [[5gty]], [[5gtz]], [[5gmp]], [[6duk]], [[6d8e]], [[5zwj]], [[5zto]], [[5y25]], [[6jrj]], [[6jrk]], [[6jrx]], [[6p1d]], [[6p1l]], [[6s89]], [[6s8a]], [[6s9b]], [[6s9c]], [[6s9d]], [[6tfu]], [[6tfv]], [[6tfw]], [[6tfy]], [[6tfz]], [[6tg0]], [[6tg1]],[[6v5n]], [[6v5p]], [[6v66]], [[6v6k]], [[6jwl]], [[6lub]], [[6v6o]], [[6wa2]], [[6wak]], [[6wxn]], [[6xl4]], [[7a6i]], [[7a6j]], [[7a6k]], [[7aei]], [[7aem]], [[7er2]], [[7k1i]], [[7ky0]], [[7ltx]], [[7oxb]], [[7u98]], [[7vra]], [[7vre]], [[8a27]], [[8a2a]], [[8a2b]], [[8a2d]] - hERBB1 (mutant)+inhibitor<br /> | + | **[[2jiu]], [[2jiv]], [[2ito]], [[2itp]], [[2itq]], [[2itt]], [[2itu]], [[2itw]], [[2itz]], [[2j6m]], [[2j5e]], [[2j5f]], [[1m17]], [[3w2o]], [[3w2p]], [[3w2q]], [[3w2r]], [[3w2s]], [[4ll0]], [[4lqm]], [[4rj4]], [[4rj5]], [[4rj6]], [[4rj7]], [[4rj8]], [[5ug9]], [[5uga]], [[5ugc]], [[5em5]], [[5em6]], [[5em7]], [[5fee]], [[5feq]], [[5gnk]], [[5hcx]], [[5hcy]], [[5hcz]], [[5hg5]], [[5hg7]], [[5hg8]], [[5hg9]], [[5hib]], [[5hic]], [[5j9y]], [[5j9z]], [[5jeb]], [[5d41]], [[5edp]], [[5edq]], [[5edr]], [[5c8k]], [[5c8m]], [[5c8n]], [[5cal]], [[5can]], [[5cao]], [[5cap]], [[5caq]], [[5cas]], [[5cau]], [[5cnn]], [[4wd5]], [[5xgm]], [[5xgn]], [[5xdk]], [[5xdl]], [[5x26]], [[5x27]], [[5x28]], [[5x2c]], [[5x2f]], [[5x2k]], [[5uwd]], [[5gty]], [[5gtz]], [[5gmp]], [[6duk]], [[6d8e]], [[5zwj]], [[5zto]], [[5y25]], [[6jrj]], [[6jrk]], [[6jrx]], [[6p1d]], [[6p1l]], [[6s89]], [[6s8a]], [[6s9b]], [[6s9c]], [[6s9d]], [[6tfu]], [[6tfv]], [[6tfw]], [[6tfy]], [[6tfz]], [[6tg0]], [[6tg1]],[[6v5n]], [[6v5p]], [[6v66]], [[6v6k]], [[6jwl]], [[6lub]], [[6v6o]], [[6wa2]], [[6wak]], [[6wxn]], [[6xl4]], [[7a6i]], [[7a6j]], [[7a6k]], [[7aei]], [[7aem]], [[7er2]], [[7k1i]], [[7ky0]], [[7ltx]], [[7oxb]], [[7u98]], [[7vra]], [[7vre]], [[7zyn]], [[7zyp]], [[7zyq]], [[8a27]], [[8a2a]], [[8a2b]], [[8a2d]], [[8d73]], [[8eme]], [[8fv3]], [[8fv4]], [[8gb4]], [[8hv1]], [[8hv2]], [[8hv3]], [[8hv4]], [[8hv5]], [[8hv6]], [[8hv7]], [[8hv8]], [[8hv9]], [[8hy7]], [[8kfq]], [[8po0]], [[8po1]], [[8po2]], [[8po3]], [[8po4]], [[8to3]], [[8to4]], [[8wd4]], [[9d3v]], [[9d3w]], [[9hbo]] - hERBB1 (mutant)+inhibitor<br /> |
| - | **[[4g5j]], [[4i23]], [[4wkq]], [[5yu9]], [[6jz0]], [[7t4i]], [[7t4j]], [[7ukv]] - hERBB1 + cancer drug<br /> | + | **[[4g5j]], [[4i23]], [[4wkq]], [[5yu9]], [[6jz0]], [[7t4i]], [[7t4j]], [[7ukv]], [[7zym]], [[8f1h]], [[8f1x]], [[8f1y]], [[8g63]] - hERBB1 + cancer drug<br /> |
| - | **[[3ug2]], [[2ity]], [[4g5p]], [[4hjo]], [[4i22]], [[4i24]], [[5y9t]], [[5x2a]], [[6jx0]], [[6jx4]], [[6jxt]], [[6lud]], [[6z4b]], [[6z4d]], [[7a2a]], [[7lgs]], [[8d73]], [[8d76]] - hERBB1 (mutant) + cancer drug<br /> | + | **[[3ug2]], [[2ity]], [[4g5p]], [[4hjo]], [[4i22]], [[4i24]], [[5y9t]], [[5x2a]], [[6jx0]], [[6jx4]], [[6jxt]], [[6lud]], [[6z4b]], [[6z4d]], [[7a2a]], [[7lgs]], [[7ukw]], [[8d73]], [[8d76]], [[8h7x]] - hERBB1 (mutant) + cancer drug<br /> |
| - | **[[7jxi]], [[7jxk]], [[7jxl]], [[7jxm]], [[7jxp]], [[7jxq]], [[7jxw]], [[7k1h]], [[7lg8]] - hERBB1 (mutant) + cancer drug + inhibitor<br /> | + | **[[7jxi]], [[7jxk]], [[7jxl]], [[7jxm]], [[7jxp]], [[7jxq]], [[7jxw]], [[7k1h]], [[7lg8]], [[8f1w]], [[8gk5]] - hERBB1 (mutant) + cancer drug + inhibitor<br /> |
**[[3b2u]] - hERBB1 +IMC-11F8 FAB fragment<br /> | **[[3b2u]] - hERBB1 +IMC-11F8 FAB fragment<br /> | ||
**[[3p0y]] - hERBB1 + FAB<br /> | **[[3p0y]] - hERBB1 + FAB<br /> | ||
Current revision
3D Structures of Epidermal Growth Factor Receptor
Updated on 01-June-2025
