4rgz
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4rgz]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermococcus_sibiricus_MM_739 Thermococcus sibiricus MM 739]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RGZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4RGZ FirstGlance]. <br> | <table><tr><td colspan='2'>[[4rgz]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermococcus_sibiricus_MM_739 Thermococcus sibiricus MM 739]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RGZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4RGZ FirstGlance]. <br> | ||
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4rgz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rgz OCA], [https://pdbe.org/4rgz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4rgz RCSB], [https://www.ebi.ac.uk/pdbsum/4rgz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4rgz ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4rgz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rgz OCA], [https://pdbe.org/4rgz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4rgz RCSB], [https://www.ebi.ac.uk/pdbsum/4rgz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4rgz ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/C6A2N7_THESM C6A2N7_THESM] | [https://www.uniprot.org/uniprot/C6A2N7_THESM C6A2N7_THESM] | ||
| - | <div style="background-color:#fffaf0;"> | ||
| - | == Publication Abstract from PubMed == | ||
| - | The crystal structure of recombinant prolidase from Thermococcus sibiricus was determined by X-ray diffraction at a resolution of 2.6 A and was found to contain a tetramer in the asymmetric unit. A protein crystal grown in microgravity using the counter-diffusion method was used for X-ray studies. The crystal belonged to space group P21221, with unit-cell parameters a = 97.60, b = 123.72, c = 136.52 A, alpha = beta = gamma = 90 degrees . The structure was refined to an Rcryst of 22.1% and an Rfree of 29.6%. The structure revealed flexible folding of the N-terminal domain of the protein as well as high variability in the positions of the bound metal ions. The coordinates of the resulting model were deposited in the Protein Data Bank as entry 4rgz. | ||
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| - | Structure of recombinant prolidase from Thermococcus sibiricus in space group P21221.,Timofeev V, Slutskaya E, Gorbacheva M, Boyko K, Rakitina T, Korzhenevskiy D, Lipkin A, Popov V Acta Crystallogr F Struct Biol Commun. 2015 Aug 1;71(Pt 8):951-7. doi:, 10.1107/S2053230X15009498. Epub 2015 Jul 28. PMID:26249680<ref>PMID:26249680</ref> | ||
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| - | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
| - | </div> | ||
| - | <div class="pdbe-citations 4rgz" style="background-color:#fffaf0;"></div> | ||
==See Also== | ==See Also== | ||
*[[Aminopeptidase 3D structures|Aminopeptidase 3D structures]] | *[[Aminopeptidase 3D structures|Aminopeptidase 3D structures]] | ||
| - | == References == | ||
| - | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Current revision
Crystal structure of recombinant prolidase from Thermococcus sibiricus at P21221 spacegroup
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