8cgy

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Current revision (08:53, 21 February 2024) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 8cgy is ON HOLD until Paper Publication
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==Trypanosoma brucei IMP dehydrogenase (ori) crystallized in High Five cells reveals native ligands ATP, GDP and phosphate. Diffraction data collection at 100 K in cellulo; XDS processing==
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<StructureSection load='8cgy' size='340' side='right'caption='[[8cgy]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8cgy]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8CGY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8CGY FirstGlance]. <br>
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Description:
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8cgy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8cgy OCA], [https://pdbe.org/8cgy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8cgy RCSB], [https://www.ebi.ac.uk/pdbsum/8cgy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8cgy ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/IMDH_TRYBB IMDH_TRYBB] Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Trypanosoma brucei]]
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[[Category: Boger J]]
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[[Category: Bourenkov G]]
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[[Category: Duden R]]
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[[Category: Harms M]]
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[[Category: Kaiser J]]
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[[Category: Lahey-Rudolph JM]]
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[[Category: Nachtschatt S]]
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[[Category: Redecke L]]
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[[Category: Schneider T]]
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[[Category: Schoenherr R]]
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[[Category: Wobbe M]]

Current revision

Trypanosoma brucei IMP dehydrogenase (ori) crystallized in High Five cells reveals native ligands ATP, GDP and phosphate. Diffraction data collection at 100 K in cellulo; XDS processing

PDB ID 8cgy

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OCA

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