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=== Key Ligand Interactions ===
=== Key Ligand Interactions ===
[[Image:Amphbindingfinal.png|275 px|right|thumb|'''Figure 3''': Electrostatic illustration of the amphipathic binding pocket of the LPA<sub>1</sub> receptor. This binding pocket was revealed by cutting away the exterior or the protein. This binding pocket, located in the interior of the protein, has both polar and nonpolar regions. The blue and red coloration highlight the positively and negatively charged regions, respectively, and the white color shows the nonpolar region of the binding pocket.]]
[[Image:Amphbindingfinal.png|275 px|right|thumb|'''Figure 3''': Electrostatic illustration of the amphipathic binding pocket of the LPA<sub>1</sub> receptor. This binding pocket was revealed by cutting away the exterior or the protein. This binding pocket, located in the interior of the protein, has both polar and nonpolar regions. The blue and red coloration highlight the positively and negatively charged regions, respectively, and the white color shows the nonpolar region of the binding pocket.]]
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=== SHOC2 and PP1C ===
=== SHOC2 and PP1C ===

Revision as of 17:09, 17 March 2023

This page, as it appeared on June 14, 2016, was featured in this article in the journal Biochemistry and Molecular Biology Education.

Contents

SHOC2-PP1C-MRAS

Introduction

Receptor Tyrosine Kinase Receptor

Figure 1: LPA receptor (blue) bound to the cell membrane. The binding pocket is highlighted in red. The added bRIL protein is highlighted in orange.
Figure 1: LPA receptor (blue) bound to the cell membrane. The binding pocket is highlighted in red. The added bRIL protein is highlighted in orange.

Lysophosphatidic Acid

Figure 2: Chemical Structure of LPA (monoacyl-sn-glycero-3-phosphate)
Figure 2: Chemical Structure of LPA (monoacyl-sn-glycero-3-phosphate)


Overall Structure

SHOC2-MRAS-PP1C 7SD0

Drag the structure with the mouse to rotate

Student Contributors

Madeline Gilbert Inaya Patel Rushda Hussein

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