Sandbox Reserved 1780

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=== TSHR Agonists and Antagonists ===
=== TSHR Agonists and Antagonists ===
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[[Image:Morph_pics2.png|250 px|right|thumb|Figure 1: Inactive form of the thyrotropin receptor shown in blue. Active form of the thyrotropin receptor shown in green. Extracellular domain rotates about the dynamic hinge region. Transmembrane domain also sees some movement.]]
 
== Active and Inactive Form ==
== Active and Inactive Form ==

Revision as of 19:18, 27 March 2023

This Sandbox is Reserved from February 27 through August 31, 2023 for use in the course CH462 Biochemistry II taught by R. Jeremy Johnson at the Butler University, Indianapolis, USA. This reservation includes Sandbox Reserved 1765 through Sandbox Reserved 1795.
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Thyroid stimulating hormone receptor bound to thyroid stimulating hormone

Drag the structure with the mouse to rotate

References

  1. ↑ 1.0 1.1 Faust B, Billesbolle CB, Suomivuori CM, Singh I, Zhang K, Hoppe N, Pinto AFM, Diedrich JK, Muftuoglu Y, Szkudlinski MW, Saghatelian A, Dror RO, Cheng Y, Manglik A. Autoantibody mimicry of hormone action at the thyrotropin receptor. Nature. 2022 Aug 8. pii: 10.1038/s41586-022-05159-1. doi:, 10.1038/s41586-022-05159-1. PMID:35940205 doi:http://dx.doi.org/10.1038/s41586-022-05159-1
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