4v7l

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Current revision (23:07, 26 March 2025) (edit) (undo)
 
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<StructureSection load='4v7l' size='340' side='right'caption='[[4v7l]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
<StructureSection load='4v7l' size='340' side='right'caption='[[4v7l]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4v7l]] is a 20 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. This structure supersedes the now removed PDB entries [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3knh 3knh], [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3kni 3kni], [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3knj 3knj] and [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3knk 3knk]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4V7L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4V7L FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4v7l]] is a 20 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_DH1 Escherichia coli DH1], [https://en.wikipedia.org/wiki/Streptomyces_californicus Streptomyces californicus] and [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4V7L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4V7L FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5OH:(2S)-AMINO[(4R,6S)-2-AMINO-6-HYDROXY-3,4,5,6-TETRAHYDROPYRIMIDIN-4-YL]ETHANOIC+ACID'>5OH</scene>, <scene name='pdbligand=DPP:DIAMINOPROPANOIC+ACID'>DPP</scene>, <scene name='pdbligand=KBE:BETA-LYSINE'>KBE</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=UAL:(2Z)-2-AMINO-3-(CARBAMOYLAMINO)PROP-2-ENOIC+ACID'>UAL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5OH:(2S)-AMINO[(4R,6S)-2-AMINO-6-HYDROXY-3,4,5,6-TETRAHYDROPYRIMIDIN-4-YL]ETHANOIC+ACID'>5OH</scene>, <scene name='pdbligand=DPP:DIAMINOPROPANOIC+ACID'>DPP</scene>, <scene name='pdbligand=KBE:BETA-LYSINE'>KBE</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=UAL:(2Z)-2-AMINO-3-(CARBAMOYLAMINO)PROP-2-ENOIC+ACID'>UAL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4v7l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4v7l OCA], [https://pdbe.org/4v7l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4v7l RCSB], [https://www.ebi.ac.uk/pdbsum/4v7l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4v7l ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4v7l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4v7l OCA], [https://pdbe.org/4v7l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4v7l RCSB], [https://www.ebi.ac.uk/pdbsum/4v7l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4v7l ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[https://www.uniprot.org/uniprot/RS2_THET8 RS2_THET8] Spans the head-body hinge region of the 30S subunit. Is loosely associated with the 30S subunit.[HAMAP-Rule:MF_00291_B]
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[https://www.uniprot.org/uniprot/RS3_THET8 RS3_THET8] Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.[HAMAP-Rule:MF_01309_B]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Escherichia coli DH1]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Streptomyces californicus]]
[[Category: Thermus thermophilus HB8]]
[[Category: Thermus thermophilus HB8]]
[[Category: Blaha G]]
[[Category: Blaha G]]
[[Category: Stanley RE]]
[[Category: Stanley RE]]

Current revision

The structures of viomycin bound to the 70S ribosome.

PDB ID 4v7l

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