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Celecoxib
From Proteopedia
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<StructureSection load='1stp' size='340' side='right' caption='Caption for this structure' scene='96/962241/Cv/1'> | <StructureSection load='1stp' size='340' side='right' caption='Caption for this structure' scene='96/962241/Cv/1'> | ||
| - | Celecoxib, sold under the brand name Celebrex among others, is a cyclooxygenase-2 (COX-2) inhibitor and nonsteroidal anti-inflammatory drug (NSAID). | + | Celecoxib, sold under the brand name Celebrex among others, is a cyclooxygenase-2 (COX-2) inhibitor and nonsteroidal anti-inflammatory drug (NSAID). It is used to treat the pain and inflammation in osteoarthritis, acute pain in adults, rheumatoid arthritis, ankylosing spondylitis, painful menstruation, and juvenile rheumatoid arthritis. See also [https://en.wikipedia.org/wiki/Celecoxib]. A highly selective reversible inhibitor of the COX-2 isoform of cyclooxygenase, celecoxib inhibits the transformation of arachidonic acid to prostaglandin precursors. Therefore, it has analgesic and anti-inflammatory properties. |
<scene name='96/962241/Bindingsite/2'>Celecoxib bound at the COX-2 active site</scene>. | <scene name='96/962241/Bindingsite/2'>Celecoxib bound at the COX-2 active site</scene>. | ||
Revision as of 10:17, 16 January 2024
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