1kn0

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1kn0.gif|left|200px]]
+
{{Seed}}
 +
[[Image:1kn0.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1kn0| PDB=1kn0 | SCENE= }}
{{STRUCTURE_1kn0| PDB=1kn0 | SCENE= }}
-
'''Crystal Structure of the human Rad52 protein'''
+
===Crystal Structure of the human Rad52 protein===
-
==Overview==
+
<!--
-
The human Rad52 protein forms a heptameric ring that catalyzes homologous pairing. The N-terminal half of Rad52 is the catalytic domain for homologous pairing, and the ring formed by the domain fragment was reported to be approximately decameric. Splicing variants of Rad52 and a yeast homolog (Rad59) are composed mostly of this domain. In this study, we determined the crystal structure of the homologous-pairing domain of human Rad52 and revealed that the domain forms an undecameric ring. Each monomer has a beta-beta-beta-alpha fold, which consists of highly conserved amino acid residues among Rad52 homologs. A mutational analysis revealed that the amino acid residues located between the beta-beta-beta-alpha fold and the characteristic hairpin loop are essential for ssDNA and dsDNA binding.
+
The line below this paragraph, {{ABSTRACT_PUBMED_12191481}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 12191481 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_12191481}}
==About this Structure==
==About this Structure==
Line 36: Line 40:
[[Category: Rsgi]]
[[Category: Rsgi]]
[[Category: Structural genomic]]
[[Category: Structural genomic]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 22:56:01 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 2 10:34:39 2008''

Revision as of 07:34, 2 July 2008

Image:1kn0.png

Template:STRUCTURE 1kn0

Crystal Structure of the human Rad52 protein

Template:ABSTRACT PUBMED 12191481

About this Structure

1KN0 is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Crystal structure of the homologous-pairing domain from the human Rad52 recombinase in the undecameric form., Kagawa W, Kurumizaka H, Ishitani R, Fukai S, Nureki O, Shibata T, Yokoyama S, Mol Cell. 2002 Aug;10(2):359-71. PMID:12191481

Page seeded by OCA on Wed Jul 2 10:34:39 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1kn0"
Personal tools