1w3s
From Proteopedia
(New page: 200px<br /> <applet load="1w3s" size="450" color="white" frame="true" align="right" spinBox="true" caption="1w3s, resolution 2.40Å" /> '''THE CRYSTAL STRUCTU...) |
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==About this Structure== | ==About this Structure== | ||
| - | 1W3S is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Deinococcus_radiodurans Deinococcus radiodurans]] with ZN as [[http://en.wikipedia.org/wiki/ligand ligand]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1W3S OCA]]. | + | 1W3S is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Deinococcus_radiodurans Deinococcus radiodurans]] with ZN as [[http://en.wikipedia.org/wiki/ligand ligand]]. Structure known Active Site: AC1. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1W3S OCA]]. |
==Reference== | ==Reference== | ||
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[[Category: sad]] | [[Category: sad]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 11:42:23 2007'' |
Revision as of 09:37, 30 October 2007
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THE CRYSTAL STRUCTURE OF RECO FROM DEINOCOCCUS RADIODURANS.
Overview
The RecFOR pathway has been shown to be essential for DNA repair through, the process of homologous recombination in bacteria and, recently, to be, important in the recovery of stalled replication forks following UV, irradiation. RecO, along with RecR, RecF, RecQ and RecJ, is a principal, actor in this fundamental DNA repair pathway. Here we present the, three-dimensional structure of a member of the RecO family. The crystal, structure of Deinococcus radiodurans RecO (drRecO) reveals possible, binding sites for DNA and for the RecO-binding proteins within its three, discrete structural regions: an N-terminal, oligonucleotide/oligosaccharide-binding domain, a helical bundle and a, zinc-finger motif. Furthermore, drRecO was found to form a stable complex, with RecR and to bind both single- ... [(full description)]
About this Structure
1W3S is a [Single protein] structure of sequence from [Deinococcus radiodurans] with ZN as [ligand]. Structure known Active Site: AC1. Full crystallographic information is available from [OCA].
Reference
Crystal structure and DNA-binding analysis of RecO from Deinococcus radiodurans., Leiros I, Timmins J, Hall DR, McSweeney S, EMBO J. 2005 Mar 9;24(5):906-18. Epub 2005 Feb 17. PMID:15719017
Page seeded by OCA on Tue Oct 30 11:42:23 2007
Categories: Deinococcus radiodurans | Single protein | Hall, D.R. | Leiros, I. | Leonard, G.A. | Mcsweeney, S.M. | Timmins, J. | ZN | Cys4 zinc finger | Dna repair | Ob-fold | Reco | Sad
