This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


Sandbox Reserved 1799

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 6: Line 6:
== Function of your protein ==
== Function of your protein ==
-
 
+
Pyrrolysyl-tRNA synthase (PylRS) is a protein found in anaerobic archaea and bacteria. PylRS facilitates the installation of pyrrolysine. It binds to the pyrrolysine substrate. This protein has two functional domains. It has a C-terminus, which is the catalytic domain (PylSc) and has a Rossmann fold, which is a tertiary fold that binds to nucleotides. The other functional domain is the N-terminus that does the tRNA binding (PylSn). These two functional domains can work together to install two noncanonical amino acids at the same time.
== Biological relevance and broader implications ==
== Biological relevance and broader implications ==
== Important amino acids==
== Important amino acids==
-
<scene name='95/954096/Amino_acids/1'>Amino Acids</scene> are an important part of the binding site.
+
 
== Structural highlights ==
== Structural highlights ==
PylRS has two domains, an N-terminal and a C-terminal. The N-terminal is responsible for tRNA-binding, PylSn. The C-terminal is the catalytic domain, PylSc.
PylRS has two domains, an N-terminal and a C-terminal. The N-terminal is responsible for tRNA-binding, PylSn. The C-terminal is the catalytic domain, PylSc.
-
The structure of PylRS appears symmetrical. There are many alpha helices as well as beta sheets and turns within.
 
-
<scene name='95/954096/Pink_-_ligands/7'> Ligands within the structure are important for this protein</scene>
 
-
This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.
+
 
-
<scene name='95/954096/Pink_-_ligands/1'>Ligands highlighted pink</scene>
+
 
-
</StructureSection>
+
== References ==
== References ==
<references/>
<references/>

Revision as of 17:10, 27 April 2023

This Sandbox is Reserved from Mar 1 through Jun 1, 2023 for use in the course CHEM 351 Biochemistry taught by Bonnie_Hall at the Grand View University, Des Moines, USA. This reservation includes Sandbox Reserved 1796 through Sandbox Reserved 1811.
To get started:
  • Click the edit this page tab at the top. Save the page after each step, then edit it again.
  • show the Scene authoring tools, create a molecular scene, and save it. Copy the green link into the page.
  • Add a description of your scene. Use the buttons above the wikitext box for bold, italics, links, headlines, etc.

More help: Help:Editing

Pyrrolysyl-tRNA synthase (PylRS)

PylRS

Drag the structure with the mouse to rotate
Retrieved from "http://52.214.119.220/wiki/index.php/Sandbox_Reserved_1799"
Personal tools