Sandbox Reserved 1797
From Proteopedia
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{{Sandbox_Reserved_CHEM351_Spring2023}}<!-- PLEASE ADD YOUR CONTENT BELOW HERE --> | {{Sandbox_Reserved_CHEM351_Spring2023}}<!-- PLEASE ADD YOUR CONTENT BELOW HERE --> | ||
| - | ==LdmS (7r8p) | + | ==ʟ-aspartate–ʟ-methionine ligase (LdmS)(7r8p)== |
<StructureSection load='7r8p' size='340' side='right' caption='LdmS' scene=''> | <StructureSection load='7r8p' size='340' side='right' caption='LdmS' scene=''> | ||
| - | This is a default text for your page ''''''. Click above on '''edit this page''' to modify. Be careful with the < and > signs. | ||
| - | You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue. | ||
== Function of your protein == | == Function of your protein == | ||
| - | <scene name='95/954094/Ldms_7r8p/1'>LdmS</scene> is found in humans. It has related mechanisms to different ATP-grasp enzymes just with different active sites. LdmS main function is to aid in the metabolism of Staphylococcal sulfur amino acids | + | <scene name='95/954094/Ldms_7r8p/1'>LdmS</scene> is found in humans infected with Staph. It exists in an open state but, can also be seen modified to a closed state. It has related mechanisms to different ATP-grasp enzymes just with different active sites. LdmS main function is to aid in the metabolism of Staphylococcal sulfur amino acids by specifically controlling Met and Cys metabolism . It can still function in settings with a lot of nutrients, or hardly any at all. This is very bad for the person infected with Staph. It is a receptor and interacts with ADP and citrate (Pederick et al, 2022). |
== Biological relevance and broader implications == | == Biological relevance and broader implications == | ||
| - | + | LdmS is important to the biology of humans. Staph infection is a serious disease that can become resistant to antibiotics making it difficult to treat (Mayo, n.d.). It is important to study how LdmS can metabolize Staphylococcal so that we can monitor how it is mutating against antibiotics. We can also see how LdmS may help with creating stronger, more resistant antibiotics for future use. | |
| + | LdmS is relevant to any disease that is catalyzed by Met and Cys, which helps host the disease in the body (Pederick et al, 2022). | ||
== Important amino acids== | == Important amino acids== | ||
Revision as of 17:29, 27 April 2023
| This Sandbox is Reserved from Mar 1 through Jun 1, 2023 for use in the course CHEM 351 Biochemistry taught by Bonnie_Hall at the Grand View University, Des Moines, USA. This reservation includes Sandbox Reserved 1796 through Sandbox Reserved 1811. |
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ʟ-aspartate–ʟ-methionine ligase (LdmS)(7r8p)
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