7fyd
From Proteopedia
(Difference between revisions)
m (Protected "7fyd" [edit=sysop:move=sysop]) |
|||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of human FABP5 in complex with 6-chloro-4-phenyl-2-propan-2-ylquinoline-3-carboxylic acid== | |
| - | + | <StructureSection load='7fyd' size='340' side='right'caption='[[7fyd]], [[Resolution|resolution]] 1.45Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7fyd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7FYD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7FYD FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=VLQ:6-chloro-4-phenyl-2-(propan-2-yl)quinoline-3-carboxylic+acid'>VLQ</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7fyd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7fyd OCA], [https://pdbe.org/7fyd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7fyd RCSB], [https://www.ebi.ac.uk/pdbsum/7fyd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7fyd ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: Benz | + | == Function == |
| - | [[Category: Ceccarelli-Simona | + | [https://www.uniprot.org/uniprot/FABP5_HUMAN FABP5_HUMAN] High specificity for fatty acids. Highest affinity for C18 chain length. Decreasing the chain length or introducing double bonds reduces the affinity. May be involved in keratinocyte differentiation. |
| - | [[Category: Obst | + | __TOC__ |
| - | [[Category: Rudolph | + | </StructureSection> |
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Benz J]] | ||
| + | [[Category: Ceccarelli-Simona M]] | ||
| + | [[Category: Ehler A]] | ||
| + | [[Category: Obst U]] | ||
| + | [[Category: Rudolph MG]] | ||
Revision as of 08:04, 14 June 2023
Crystal Structure of human FABP5 in complex with 6-chloro-4-phenyl-2-propan-2-ylquinoline-3-carboxylic acid
| |||||||||||
