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7g0b
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of human FABP5 in complex with 7-bromo-1-methyl-5-phenyl-2,3,4,5-tetrahydro-1-benzazepine-4-carboxylic acid== | |
| - | + | <StructureSection load='7g0b' size='340' side='right'caption='[[7g0b]], [[Resolution|resolution]] 1.47Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7g0b]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7G0B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7G0B FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=WK0:(4S,5S)-7-bromo-1-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-1-benzazepine-4-carboxylic+acid'>WK0</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7g0b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7g0b OCA], [https://pdbe.org/7g0b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7g0b RCSB], [https://www.ebi.ac.uk/pdbsum/7g0b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7g0b ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: Benz | + | == Function == |
| - | [[Category: Ceccarelli-Simona | + | [https://www.uniprot.org/uniprot/FABP5_HUMAN FABP5_HUMAN] High specificity for fatty acids. Highest affinity for C18 chain length. Decreasing the chain length or introducing double bonds reduces the affinity. May be involved in keratinocyte differentiation. |
| - | [[Category: Obst | + | __TOC__ |
| - | [[Category: Rudolph | + | </StructureSection> |
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Benz J]] | ||
| + | [[Category: Ceccarelli-Simona M]] | ||
| + | [[Category: Ehler A]] | ||
| + | [[Category: Obst U]] | ||
| + | [[Category: Rudolph MG]] | ||
Revision as of 08:07, 14 June 2023
Crystal Structure of human FABP5 in complex with 7-bromo-1-methyl-5-phenyl-2,3,4,5-tetrahydro-1-benzazepine-4-carboxylic acid
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