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8sep
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Cryo-EM Structure of RyR1 + ADP== | |
| - | + | <StructureSection load='8sep' size='340' side='right'caption='[[8sep]], [[Resolution|resolution]] 3.57Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8sep]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8SEP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8SEP FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8sep FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8sep OCA], [https://pdbe.org/8sep PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8sep RCSB], [https://www.ebi.ac.uk/pdbsum/8sep PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8sep ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/GST26_SCHJA GST26_SCHJA] Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. GST isoenzymes appear to play a central role in the parasite detoxification system. Other functions are also suspected including a role in increasing the solubility of haematin in the parasite gut.[https://www.uniprot.org/uniprot/FKB1B_HUMAN FKB1B_HUMAN] Has the potential to contribute to the immunosuppressive and toxic effects of FK506 and rapamycin. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Oryctolagus cuniculus]] | ||
| + | [[Category: Berezuk AM]] | ||
| + | [[Category: Cholak S]] | ||
| + | [[Category: Haji-Ghassemi O]] | ||
| + | [[Category: Saville JW]] | ||
| + | [[Category: Subramaniam S]] | ||
| + | [[Category: Tuttle KS]] | ||
| + | [[Category: Van Petegem F]] | ||
| + | [[Category: Zhu X]] | ||
Revision as of 04:09, 25 May 2023
Cryo-EM Structure of RyR1 + ADP
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