7trs
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[7trs]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7TRS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7TRS FirstGlance]. <br> | <table><tr><td colspan='2'>[[7trs]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7TRS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7TRS FirstGlance]. <br> | ||
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACH:ACETYLCHOLINE'>ACH</scene></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.8Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACH:ACETYLCHOLINE'>ACH</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7trs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7trs OCA], [https://pdbe.org/7trs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7trs RCSB], [https://www.ebi.ac.uk/pdbsum/7trs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7trs ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7trs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7trs OCA], [https://pdbe.org/7trs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7trs RCSB], [https://www.ebi.ac.uk/pdbsum/7trs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7trs ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | [https://www.uniprot.org/uniprot/ | + | [https://www.uniprot.org/uniprot/ACM4_HUMAN ACM4_HUMAN] The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is inhibition of adenylate cyclase. |
| - | == | + | |
| - | + | ==See Also== | |
| + | *[[Muscarinic acetylcholine receptor|Muscarinic acetylcholine receptor]] | ||
| + | *[[Transducin 3D structures|Transducin 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Current revision
Human M4 muscarinic acetylcholine receptor complex with Gi1 and the endogenous agonist acetylcholine
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Categories: Homo sapiens | Large Structures | Mus musculus | Belousoff MJ | Danev R | Glukhova A | Mobbs JI | Sexton PM | Thal DM | Vuckovic Z
