4zyi

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Current revision (11:01, 10 January 2024) (edit) (undo)
 
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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4zyi]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZYI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ZYI FirstGlance]. <br>
<table><tr><td colspan='2'>[[4zyi]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZYI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ZYI FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4TH:(S)-7-((R)-SEC-BUTOXY)-1-(4-CHLOROPHENYL)-6-METHOXY-2-(4-(METHYL(PYRIDIN-4-YLMETHYL)AMINO)PHENYL)-1,2-DIHYDROISOQUINOLIN-3(4H)-ONE'>4TH</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.67&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4TH:(S)-7-((R)-SEC-BUTOXY)-1-(4-CHLOROPHENYL)-6-METHOXY-2-(4-(METHYL(PYRIDIN-4-YLMETHYL)AMINO)PHENYL)-1,2-DIHYDROISOQUINOLIN-3(4H)-ONE'>4TH</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4zyi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zyi OCA], [https://pdbe.org/4zyi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4zyi RCSB], [https://www.ebi.ac.uk/pdbsum/4zyi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4zyi ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4zyi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zyi OCA], [https://pdbe.org/4zyi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4zyi RCSB], [https://www.ebi.ac.uk/pdbsum/4zyi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4zyi ProSAT]</span></td></tr>
</table>
</table>

Current revision

Discovery of NVP-CGM097 - a highly potent and selective MDM2 inhibitor undergoing phase 1 clinical trials in p53wt tumors: Hdm2 (MDM2) complexed with cpd2

PDB ID 4zyi

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