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8sl1

From Proteopedia

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Current revision (12:06, 8 November 2023) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 8sl1 is ON HOLD until Paper Publication
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==Cryo-EM structure of PAPP-A2==
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<StructureSection load='8sl1' size='340' side='right'caption='[[8sl1]], [[Resolution|resolution]] 3.13&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8sl1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8SL1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8SL1 FirstGlance]. <br>
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Description:
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.13&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8sl1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8sl1 OCA], [https://pdbe.org/8sl1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8sl1 RCSB], [https://www.ebi.ac.uk/pdbsum/8sl1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8sl1 ProSAT]</span></td></tr>
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</table>
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== Disease ==
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[https://www.uniprot.org/uniprot/PAPP2_HUMAN PAPP2_HUMAN] The disease is caused by variants affecting the gene represented in this entry.
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== Function ==
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[https://www.uniprot.org/uniprot/PAPP2_HUMAN PAPP2_HUMAN] Metalloproteinase which specifically cleaves insulin-like growth factor binding protein (IGFBP)-5 at the '163-Ser-|-Lys-164' bond. Shows limited proteolysis toward IGFBP-3.<ref>PMID:11264294</ref> <ref>PMID:26902202</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Bratkowski MA]]
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[[Category: Eaton D]]
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[[Category: Hao Q]]
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[[Category: Judge RA]]
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[[Category: Stoll VS]]

Current revision

Cryo-EM structure of PAPP-A2

PDB ID 8sl1

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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