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1l0s

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[[Image:1l0s.jpg|left|200px]]
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{{Seed}}
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[[Image:1l0s.png|left|200px]]
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{{STRUCTURE_1l0s| PDB=1l0s | SCENE= }}
{{STRUCTURE_1l0s| PDB=1l0s | SCENE= }}
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'''Choristoneura fumiferana (spruce budworm) antifreeze protein isoform 337'''
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===Choristoneura fumiferana (spruce budworm) antifreeze protein isoform 337===
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==Overview==
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Reported here is the 2.3 A resolution crystal structure of spruce budworm (Choristoneura fumiferana) antifreeze protein (CfAFP), solved by single anomalous scattering. The structure reveals an extremely regular left-handed beta-helical platform consisting of 15-amino acid loops with a repetitive Thr-X-Thr motif displayed on one of the helix's three faces. This motif results in a two-dimensional array of threonine residues in an identical orientation to those in the nonhomologous, right-handed beta-helical beetle AFP from Tenebrio molitor (TmAFP). The CfAFP structure led us to reevaluate our ice binding model, and the analysis of three possible modes of docking gives rise to a binding mechanism based on surface complementarity. This general mechanism is applicable to both fish and insect AFPs.
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The line below this paragraph, {{ABSTRACT_PUBMED_12015145}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 12015145 is the PubMed ID number.
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{{ABSTRACT_PUBMED_12015145}}
==About this Structure==
==About this Structure==
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[[Category: Iodination]]
[[Category: Iodination]]
[[Category: Left-handed beta-helix]]
[[Category: Left-handed beta-helix]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 23:24:46 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 2 11:27:13 2008''

Revision as of 08:27, 2 July 2008

Template:STRUCTURE 1l0s

Choristoneura fumiferana (spruce budworm) antifreeze protein isoform 337

Template:ABSTRACT PUBMED 12015145

About this Structure

1L0S is a Single protein structure of sequence from Choristoneura fumiferana. Full crystallographic information is available from OCA.

Reference

Crystal structure of beta-helical antifreeze protein points to a general ice binding model., Leinala EK, Davies PL, Jia Z, Structure. 2002 May;10(5):619-27. PMID:12015145

Page seeded by OCA on Wed Jul 2 11:27:13 2008

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