This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1l1w

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1l1w.gif|left|200px]]
+
{{Seed}}
 +
[[Image:1l1w.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1l1w| PDB=1l1w | SCENE= }}
{{STRUCTURE_1l1w| PDB=1l1w | SCENE= }}
-
'''NMR structure of a SRP19 binding domain in human SRP RNA'''
+
===NMR structure of a SRP19 binding domain in human SRP RNA===
-
==Overview==
+
<!--
-
Assembly of the human signal recognition particle (SRP) requires SRP19 protein to bind to helices 6 and 8 of SRP RNA. In the present study, structure of a 29-mer RNA composing the SRP19 binding site in helix 6 was determined by NMR spectroscopy. The two A:C mismatches were continuously stacked to each other and formed wobble type A:C base pairs. The GGAG tetraloop in helix 6 was found to adopt a similar conformation to that of GNRA tetraloop, suggesting that these tetraloops are included in an extensive new motif GNRR. Compared with the crystal structure of helix 6 in complex with SRP19 determined previously, the GGAG tetraloop in the complex was found to adopt a similar conformation to the free form, although the loop structure becomes more open upon SRP19 binding. Thus, SRP19 is thought to recognize the overall fold of the GGAG loop.
+
The line below this paragraph, {{ABSTRACT_PUBMED_12153712}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 12153712 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_12153712}}
==About this Structure==
==About this Structure==
-
Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L1W OCA].
+
Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L1W OCA].
==Reference==
==Reference==
Line 29: Line 33:
[[Category: Rna hairpin]]
[[Category: Rna hairpin]]
[[Category: Tetraloop]]
[[Category: Tetraloop]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 23:26:58 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 2 11:31:09 2008''

Revision as of 08:31, 2 July 2008

Image:1l1w.png

Template:STRUCTURE 1l1w

NMR structure of a SRP19 binding domain in human SRP RNA

Template:ABSTRACT PUBMED 12153712

About this Structure

Full experimental information is available from OCA.

Reference

Solution structure of a SRP19 binding domain in human SRP RNA., Sakamoto T, Morita S, Tabata K, Nakamura K, Kawai G, J Biochem. 2002 Aug;132(2):177-82. PMID:12153712

Page seeded by OCA on Wed Jul 2 11:31:09 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1l1w"
Personal tools