This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
8slt
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of human STEP (PTPN5) at physiological temperature (310 K) and ambient pressure (0.1 MPa)== | |
| - | + | <StructureSection load='8slt' size='340' side='right'caption='[[8slt]], [[Resolution|resolution]] 1.96Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8slt]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8SLT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8SLT FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8slt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8slt OCA], [https://pdbe.org/8slt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8slt RCSB], [https://www.ebi.ac.uk/pdbsum/8slt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8slt ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: Ebrahim | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/PTN5_HUMAN PTN5_HUMAN] May regulate the activity of several effector molecules involved in synaptic plasticity and neuronal cell survival, including MAPKs, Src family kinases and NMDA receptors.<ref>PMID:21777200</ref> |
| - | [[Category: | + | == References == |
| - | [[Category: | + | <references/> |
| - | [[Category: | + | __TOC__ |
| - | [[Category: Kim | + | </StructureSection> |
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Ebrahim A]] | ||
| + | [[Category: Finke AD]] | ||
| + | [[Category: Guerrero L]] | ||
| + | [[Category: Huang Q]] | ||
| + | [[Category: Keedy DA]] | ||
| + | [[Category: Kim M]] | ||
| + | [[Category: Riley BT]] | ||
Revision as of 09:43, 21 June 2023
Crystal structure of human STEP (PTPN5) at physiological temperature (310 K) and ambient pressure (0.1 MPa)
| |||||||||||
Categories: Homo sapiens | Large Structures | Ebrahim A | Finke AD | Guerrero L | Huang Q | Keedy DA | Kim M | Riley BT
