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1l2n

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{{STRUCTURE_1l2n| PDB=1l2n | SCENE= }}
{{STRUCTURE_1l2n| PDB=1l2n | SCENE= }}
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'''Smt3 Solution Structure'''
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===Smt3 Solution Structure===
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==Overview==
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Smt3 belongs to a growing family of ubiquitin-related proteins involved in posttranslational protein modification. Independent studies demonstrate an essential function of Smt3 in the regulation of nucleocytoplasmic transport, and suggest a role in cell-cycle regulation. Here we report the high-resolution NMR structure of yeast Smt3 in the complex free form. Our comparison of the Smt3 NMR structure with the Smt3 crystal structure in complex with the C-Terminal Ulp1 protease domain revealed large structural differences in the binding surface, which is also involved in the Smt3-Ubc-9 interaction detected by NMR. The structural differences in the region indicate the important functions of conserved residues in less structurally defined sequences.
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{{ABSTRACT_PUBMED_12021447}}
==About this Structure==
==About this Structure==
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1L2N is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L2N OCA].
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1L2N is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L2N OCA].
==Reference==
==Reference==
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[[Category: Structure]]
[[Category: Structure]]
[[Category: Ubiquitin-like protein]]
[[Category: Ubiquitin-like protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 23:28:25 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 2 11:33:56 2008''

Revision as of 08:33, 2 July 2008

Image:1l2n.png

Template:STRUCTURE 1l2n

Smt3 Solution Structure

Template:ABSTRACT PUBMED 12021447

About this Structure

1L2N is a Single protein structure of sequence from Saccharomyces cerevisiae. Full experimental information is available from OCA.

Reference

Solution structure of a yeast ubiquitin-like protein Smt3: the role of structurally less defined sequences in protein-protein recognitions., Sheng W, Liao X, Protein Sci. 2002 Jun;11(6):1482-91. PMID:12021447

Page seeded by OCA on Wed Jul 2 11:33:56 2008

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