8tar
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==APC/C-CDH1-UBE2C-Ubiquitin-CyclinB-NTD== | |
| - | + | <StructureSection load='8tar' size='340' side='right'caption='[[8tar]], [[Resolution|resolution]] 4.00Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8tar]] is a 13 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8TAR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8TAR FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8tar FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8tar OCA], [https://pdbe.org/8tar PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8tar RCSB], [https://www.ebi.ac.uk/pdbsum/8tar PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8tar ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/APC1_HUMAN APC1_HUMAN] Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.<ref>PMID:18485873</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Amann SJ]] | ||
| + | [[Category: Bodrug T]] | ||
| + | [[Category: Bolhuis DL]] | ||
| + | [[Category: Bonacci T]] | ||
| + | [[Category: Brown NG]] | ||
| + | [[Category: Cui L]] | ||
| + | [[Category: Emanuele MJ]] | ||
| + | [[Category: Grishkovskaya I]] | ||
| + | [[Category: Hahn KM]] | ||
| + | [[Category: Harrison JS]] | ||
| + | [[Category: Haselbach D]] | ||
| + | [[Category: Liu B]] | ||
| + | [[Category: Martinez-Chacin RC]] | ||
| + | [[Category: Paulakonis E]] | ||
| + | [[Category: Pinkin N]] | ||
| + | [[Category: Roscow O]] | ||
| + | [[Category: Steimel JP]] | ||
| + | [[Category: Welsh KA]] | ||
| + | [[Category: Xu P]] | ||
| + | [[Category: Zhang W]] | ||
| + | [[Category: Zhong E]] | ||
Current revision
APC/C-CDH1-UBE2C-Ubiquitin-CyclinB-NTD
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Categories: Homo sapiens | Large Structures | Amann SJ | Bodrug T | Bolhuis DL | Bonacci T | Brown NG | Cui L | Emanuele MJ | Grishkovskaya I | Hahn KM | Harrison JS | Haselbach D | Liu B | Martinez-Chacin RC | Paulakonis E | Pinkin N | Roscow O | Steimel JP | Welsh KA | Xu P | Zhang W | Zhong E
