1log

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1log.jpg|left|200px]]
+
{{Seed}}
 +
[[Image:1log.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1log| PDB=1log | SCENE= }}
{{STRUCTURE_1log| PDB=1log | SCENE= }}
-
'''X-RAY STRUCTURE OF A (ALPHA-MAN(1-3)BETA-MAN(1-4)GLCNAC)-LECTIN COMPLEX AT 2.1 ANGSTROMS RESOLUTION'''
+
===X-RAY STRUCTURE OF A (ALPHA-MAN(1-3)BETA-MAN(1-4)GLCNAC)-LECTIN COMPLEX AT 2.1 ANGSTROMS RESOLUTION===
-
==Overview==
+
<!--
-
We describe herein the high resolution refined x-ray structure of a trisaccharide, which is a part of the N-acetyllactosamine type glycan found in the majority of the N-glycosyl-proteins, complexed to the isolectin I. According to the potentials used by Imberty et al. (Imburty, A., Gerber, S., Tran, V., and Perez, S. (1990) Glycoconjugate J. 7, 27-54) the trisaccharide is in a low-energy state. Only one mannose moiety establishes direct hydrogen bonds with the lectin, as it is the case for monosaccharide-lectin complexes. The comparison of our trisaccharide with the one determined in solution by Warin et al. (Warin, V., Baert, F., Fouret, R., Strecker, G., Fournet, B., and Montreuil, J. (1979) Carbohydr. Res. 76, 11-22) shows that both adopt roughly the same conformation. The differences in these two sugar structures allow us to assign the role of water molecules present in the vicinity of our trisaccharide for the stabilization of this sugar-lectin complex.
+
The line below this paragraph, {{ABSTRACT_PUBMED_2211692}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 2211692 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_2211692}}
==About this Structure==
==About this Structure==
Line 25: Line 29:
[[Category: Cambillau, C.]]
[[Category: Cambillau, C.]]
[[Category: Lectin]]
[[Category: Lectin]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 00:07:03 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 2 21:35:25 2008''

Revision as of 18:35, 2 July 2008

Template:STRUCTURE 1log

X-RAY STRUCTURE OF A (ALPHA-MAN(1-3)BETA-MAN(1-4)GLCNAC)-LECTIN COMPLEX AT 2.1 ANGSTROMS RESOLUTION

Template:ABSTRACT PUBMED 2211692

About this Structure

1LOG is a Protein complex structure of sequences from Lathyrus ochrus. Full crystallographic information is available from OCA.

Reference

X-ray structure of a (alpha-Man(1-3)beta-Man(1-4)GlcNAc)-lectin complex at 2.1-A resolution. The role of water in sugar-lectin interaction., Bourne Y, Rouge P, Cambillau C, J Biol Chem. 1990 Oct 25;265(30):18161-5. PMID:2211692

Page seeded by OCA on Wed Jul 2 21:35:25 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools