1lri

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[[Image:1lri.gif|left|200px]]
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{{Seed}}
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{{STRUCTURE_1lri| PDB=1lri | SCENE= }}
{{STRUCTURE_1lri| PDB=1lri | SCENE= }}
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'''BETA-CRYPTOGEIN-CHOLESTEROL COMPLEX'''
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===BETA-CRYPTOGEIN-CHOLESTEROL COMPLEX===
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==Overview==
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Cryptogein is a small 10 kDa elicitor produced by the phytoparasitic oomycete Phytophthora cryptogea. The protein also displays a sterol carrier activity. The native protein crystallizes in space group P4(1)22, with unit-cell parameters a = b = 46.51, c = 134.9 A (diffraction limit: 2.1 A). Its complex with cholesterol crystallizes in space group C222(1), with unit-cell parameters a = 30.96, b = 94.8, c = 65.3 A and a resolution enhanced to 1.45 A. The large inner non-specific hydrophobic cavity is able to accommodate a large variety of 3-beta-hydroxy sterols. Cryptogein probably acts as a sterol shuttle helping the pathogen to grow and complete its life cycle.
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(as it appears on PubMed at http://www.pubmed.gov), where 12198300 is the PubMed ID number.
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{{ABSTRACT_PUBMED_12198300}}
==About this Structure==
==About this Structure==
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[[Category: Cryptogein]]
[[Category: Cryptogein]]
[[Category: Sterol carrier protein]]
[[Category: Sterol carrier protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 00:12:47 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 2 21:52:49 2008''

Revision as of 18:52, 2 July 2008

Image:1lri.png

Template:STRUCTURE 1lri

BETA-CRYPTOGEIN-CHOLESTEROL COMPLEX

Template:ABSTRACT PUBMED 12198300

About this Structure

1LRI is a Single protein structure of sequence from Phytophthora cryptogea. Full crystallographic information is available from OCA.

Reference

The 1.45 A resolution structure of the cryptogein-cholesterol complex: a close-up view of a sterol carrier protein (SCP) active site., Lascombe MB, Ponchet M, Venard P, Milat ML, Blein JP, Prange T, Acta Crystallogr D Biol Crystallogr. 2002 Sep;58(Pt 9):1442-7. Epub 2002, Aug 23. PMID:12198300

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