This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1m56

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1m56.gif|left|200px]]
+
{{Seed}}
 +
[[Image:1m56.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1m56| PDB=1m56 | SCENE= }}
{{STRUCTURE_1m56| PDB=1m56 | SCENE= }}
-
'''Structure of cytochrome c oxidase from Rhodobactor sphaeroides (Wild Type)'''
+
===Structure of cytochrome c oxidase from Rhodobactor sphaeroides (Wild Type)===
-
==Overview==
+
<!--
-
The structure of cytochrome c oxidase from Rhodobacter sphaeroides has been solved at 2.3/2.8A (anisotropic resolution). This high-resolution structure revealed atomic details of a bacterial terminal oxidase including water molecule positions and a potential oxygen pathway, which has not been reported in other oxidase structures. A comparative study of the wild-type and the EQ(I-286) mutant enzyme revealed structural rearrangements around E(I-286) that could be crucial for proton transfer in this enzyme. In the structure of the mutant enzyme, EQ(I-286), which cannot transfer protons during oxygen reduction, the side-chain of Q(I-286) does not have the hydrogen bond to the carbonyl oxygen of M(I-107) that is seen in the wild-type structure. Furthermore, the Q(I-286) mutant has a different arrangement of water molecules and residues in the vicinity of the Q side-chain. These differences between the structures could reflect conformational changes that take place upon deprotonation of E(I-286) during turnover of the wild-type enzyme, which could be part of the proton-pumping machinery of the enzyme.
+
The line below this paragraph, {{ABSTRACT_PUBMED_12144789}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 12144789 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_12144789}}
==About this Structure==
==About this Structure==
Line 30: Line 34:
[[Category: Tornroth, S.]]
[[Category: Tornroth, S.]]
[[Category: Membrane protein]]
[[Category: Membrane protein]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 00:38:42 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 2 23:14:08 2008''

Revision as of 20:14, 2 July 2008

Image:1m56.png

Template:STRUCTURE 1m56

Structure of cytochrome c oxidase from Rhodobactor sphaeroides (Wild Type)

Template:ABSTRACT PUBMED 12144789

About this Structure

1M56 is a Protein complex structure of sequences from Rhodobacter sphaeroides. Full crystallographic information is available from OCA.

Reference

The X-ray crystal structures of wild-type and EQ(I-286) mutant cytochrome c oxidases from Rhodobacter sphaeroides., Svensson-Ek M, Abramson J, Larsson G, Tornroth S, Brzezinski P, Iwata S, J Mol Biol. 2002 Aug 9;321(2):329-39. PMID:12144789

Page seeded by OCA on Wed Jul 2 23:14:08 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1m56"
Personal tools