1m7b

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{{STRUCTURE_1m7b| PDB=1m7b | SCENE= }}
{{STRUCTURE_1m7b| PDB=1m7b | SCENE= }}
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'''Crystal structure of Rnd3/RhoE: functional implications'''
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===Crystal structure of Rnd3/RhoE: functional implications===
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==Overview==
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The Rnd proteins constitute an exceptional subfamily within the Rho GTPase family. They possess extended chains at both termini and four prominent amino acid deviations causing GTPase deficiency. Herein, we report the crystal structure of the Rnd3/RhoE G-domain (amino acids 19-200) at 2.0 A resolution. This is the first GTP-structure of a Rho family member which reveals a similar fold but striking differences from RhoA concerning (i) GTPase center, (ii) charge distribution at several surface areas, (iii) C3-transferase binding site and (iv) interacting interfaces towards RhoA regulators and effectors.
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(as it appears on PubMed at http://www.pubmed.gov), where 12163169 is the PubMed ID number.
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{{ABSTRACT_PUBMED_12163169}}
==About this Structure==
==About this Structure==
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[[Category: Vetter, I R.]]
[[Category: Vetter, I R.]]
[[Category: Small gtpase]]
[[Category: Small gtpase]]
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Revision as of 20:22, 2 July 2008

Image:1m7b.png

Template:STRUCTURE 1m7b

Crystal structure of Rnd3/RhoE: functional implications

Template:ABSTRACT PUBMED 12163169

About this Structure

1M7B is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Crystal structure of Rnd3/RhoE: functional implications., Fiegen D, Blumenstein L, Stege P, Vetter IR, Ahmadian MR, FEBS Lett. 2002 Aug 14;525(1-3):100-4. PMID:12163169

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