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1mcp

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[[Image:1mcp.jpg|left|200px]]
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{{STRUCTURE_1mcp| PDB=1mcp | SCENE= }}
{{STRUCTURE_1mcp| PDB=1mcp | SCENE= }}
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'''PHOSPHOCHOLINE BINDING IMMUNOGLOBULIN FAB MC/PC603. AN X-RAY DIFFRACTION STUDY AT 2.7 ANGSTROMS'''
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===PHOSPHOCHOLINE BINDING IMMUNOGLOBULIN FAB MC/PC603. AN X-RAY DIFFRACTION STUDY AT 2.7 ANGSTROMS===
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==Overview==
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The crystal structure of the Fab of McPC603, a phosphocholine-binding mouse myeloma protein, has been refined at 2.7 A resolution by a combination of restrained least-squares refinement and molecular modeling. The overall structure remains as previously reported, with an elbow bend angle between the variable and constant modules of 133 degrees. Some adjustments have been made in the structure of the loops as a result of the refinement. The hypervariable loops are all visible in the electron density map with the exception of three residues in the first hypervariable loop of the light chain. A sulfate ion occupies the site of binding of the phosphate moiety of phosphocholine.
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The line below this paragraph, {{ABSTRACT_PUBMED_3097327}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 3097327 is the PubMed ID number.
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{{ABSTRACT_PUBMED_3097327}}
==About this Structure==
==About this Structure==
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[[Category: Satow, Y.]]
[[Category: Satow, Y.]]
[[Category: Immunoglobulin]]
[[Category: Immunoglobulin]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 00:53:36 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 2 23:41:27 2008''

Revision as of 20:41, 2 July 2008

Image:1mcp.png

Template:STRUCTURE 1mcp

PHOSPHOCHOLINE BINDING IMMUNOGLOBULIN FAB MC/PC603. AN X-RAY DIFFRACTION STUDY AT 2.7 ANGSTROMS

Template:ABSTRACT PUBMED 3097327

About this Structure

1MCP is a Protein complex structure of sequences from Mus musculus. Full crystallographic information is available from OCA.

Reference

Phosphocholine binding immunoglobulin Fab McPC603. An X-ray diffraction study at 2.7 A., Satow Y, Cohen GH, Padlan EA, Davies DR, J Mol Biol. 1986 Aug 20;190(4):593-604. PMID:3097327

Page seeded by OCA on Wed Jul 2 23:41:27 2008

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