8q7n
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==cryo-EM structure of the human spliceosomal B complex protomer (tri-snRNP core region)== | |
| - | + | <StructureSection load='8q7n' size='340' side='right'caption='[[8q7n]], [[Resolution|resolution]] 3.10Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8q7n]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8Q7N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8Q7N FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.1Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8q7n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8q7n OCA], [https://pdbe.org/8q7n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8q7n RCSB], [https://www.ebi.ac.uk/pdbsum/8q7n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8q7n ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/SF3A1_HUMAN SF3A1_HUMAN] Subunit of the splicing factor SF3A required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Dybkov O]] | ||
| + | [[Category: Kumar V]] | ||
| + | [[Category: Luehrmann R]] | ||
| + | [[Category: Stark H]] | ||
| + | [[Category: Urlaub H]] | ||
| + | [[Category: Will CL]] | ||
| + | [[Category: Zhang Z]] | ||
Revision as of 11:29, 24 January 2024
cryo-EM structure of the human spliceosomal B complex protomer (tri-snRNP core region)
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Categories: Homo sapiens | Large Structures | Dybkov O | Kumar V | Luehrmann R | Stark H | Urlaub H | Will CL | Zhang Z
