8tle
From Proteopedia
(Difference between revisions)
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- | '''Unreleased structure''' | ||
- | + | ==CDCA7 (Mouse) Binds Non-B-form 36-mer DNA oligo (sg C2-Form 1)== | |
- | + | <StructureSection load='8tle' size='340' side='right'caption='[[8tle]], [[Resolution|resolution]] 2.08Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[8tle]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8TLE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8TLE FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.08Å</td></tr> | |
- | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8tle FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8tle OCA], [https://pdbe.org/8tle PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8tle RCSB], [https://www.ebi.ac.uk/pdbsum/8tle PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8tle ProSAT]</span></td></tr> |
+ | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/CDCA7_MOUSE CDCA7_MOUSE] Participates in MYC-mediated cell transformation and apoptosis; induces anchorage-independent growth and clonogenicity in lymphoblastoid cells. Insufficient to induce tumorigenicity when overexpressed but contributes to MYC-mediated tumorigenesis. May play a role as transcriptional regulator (By similarity).<ref>PMID:16580749</ref> | ||
+ | == References == | ||
+ | <references/> | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Large Structures]] | ||
+ | [[Category: Mus musculus]] | ||
+ | [[Category: Cheng X]] | ||
+ | [[Category: Horton JR]] | ||
+ | [[Category: Ren R]] |
Current revision
CDCA7 (Mouse) Binds Non-B-form 36-mer DNA oligo (sg C2-Form 1)
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