1aop
From Proteopedia
(New page: 200px<br /> <applet load="1aop" size="450" color="white" frame="true" align="right" spinBox="true" caption="1aop, resolution 1.60Å" /> '''SULFITE REDUCTASE S...) |
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==About this Structure== | ==About this Structure== | ||
| - | 1AOP is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]] with PO4, K, SF4 and SRM as [[http://en.wikipedia.org/wiki/ligands ligands]]. This structure superseeds the now removed PDB entry 1GEO. Active as [[http://en.wikipedia.org/wiki/ ]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.8.1.2 1.8.1.2]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1AOP OCA]]. | + | 1AOP is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]] with PO4, K, SF4 and SRM as [[http://en.wikipedia.org/wiki/ligands ligands]]. This structure superseeds the now removed PDB entry 1GEO. Active as [[http://en.wikipedia.org/wiki/Sulfite_reductase_(NADPH) Sulfite reductase (NADPH)]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.8.1.2 1.8.1.2]]. Structure known Active Sites: ACT and BRG. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1AOP OCA]]. |
==Reference== | ==Reference== | ||
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[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
| + | [[Category: Sulfite reductase (NADPH)]] | ||
[[Category: Crane, B.R.]] | [[Category: Crane, B.R.]] | ||
[[Category: Getzoff, E.D.]] | [[Category: Getzoff, E.D.]] | ||
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[[Category: snirr]] | [[Category: snirr]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 11:45:28 2007'' |
Revision as of 09:40, 30 October 2007
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SULFITE REDUCTASE STRUCTURE AT 1.6 ANGSTROM RESOLUTION
Overview
Fundamental chemical transformations for biogeochemical cycling of sulfur, and nitrogen are catalyzed by sulfite and nitrite reductases. The, crystallographic structure of Escherichia coli sulfite reductase, hemoprotein (SiRHP), which catalyzes the concerted six-electron reductions, of sulfite to sulfide and nitrite to ammonia, was solved with, multiwavelength anomalous diffraction (MAD) of the native siroheme and, Fe4S4 cluster cofactors, multiple isomorphous replacement, and, selenomethionine sequence markers. Twofold symmetry within the, 64-kilodalton polypeptide generates a distinctive three-domain alpha/beta, fold that controls cofactor assembly and reactivity. Homology regions, conserved between the symmetry-related halves of SiRHP and among other, sulfite and nitrite reductases ... [(full description)]
About this Structure
1AOP is a [Single protein] structure of sequence from [Escherichia coli] with PO4, K, SF4 and SRM as [ligands]. This structure superseeds the now removed PDB entry 1GEO. Active as [Sulfite reductase (NADPH)], with EC number [1.8.1.2]. Structure known Active Sites: ACT and BRG. Full crystallographic information is available from [OCA].
Reference
Sulfite reductase structure at 1.6 A: evolution and catalysis for reduction of inorganic anions., Crane BR, Siegel LM, Getzoff ED, Science. 1995 Oct 6;270(5233):59-67. PMID:7569952[[Category: [4fe-4s]]]
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