1mp6

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[[Image:1mp6.jpg|left|200px]]
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{{STRUCTURE_1mp6| PDB=1mp6 | SCENE= }}
{{STRUCTURE_1mp6| PDB=1mp6 | SCENE= }}
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'''Structure of the transmembrane region of the M2 protein H+ channel by solid state NMR spectroscopy'''
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===Structure of the transmembrane region of the M2 protein H+ channel by solid state NMR spectroscopy===
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==Overview==
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The transmembrane domain of the M2 protein from influenza A virus forms a nearly uniform and ideal helix in a liquid crystalline bilayer environment. The exposure of the hydrophilic backbone structure is minimized through uniform hydrogen bond geometry imposed by the low dielectric lipid environment. A high-resolution structure of the monomer backbone and a detailed description of its orientation with respect to the bilayer were achieved using orientational restraints from solid-state NMR. With this unique information, the tetrameric structure of this H(+) channel is constrained substantially. Features of numerous published models are discussed in light of the experimental structure of the monomer and derived features of the tetrameric bundle.
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The line below this paragraph, {{ABSTRACT_PUBMED_11604531}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 11604531 is the PubMed ID number.
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{{ABSTRACT_PUBMED_11604531}}
==About this Structure==
==About this Structure==
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1MP6 is a [[Single protein]] structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MP6 OCA].
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1MP6 is a [[Single protein]] structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MP6 OCA].
==Reference==
==Reference==
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[[Category: Membrane protein structure]]
[[Category: Membrane protein structure]]
[[Category: Solid state nmr]]
[[Category: Solid state nmr]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 01:32:58 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jul 3 00:39:19 2008''

Revision as of 21:39, 2 July 2008

Template:STRUCTURE 1mp6

Structure of the transmembrane region of the M2 protein H+ channel by solid state NMR spectroscopy

Template:ABSTRACT PUBMED 11604531

About this Structure

1MP6 is a Single protein structure. Full experimental information is available from OCA.

Reference

Structure of the transmembrane region of the M2 protein H(+) channel., Wang J, Kim S, Kovacs F, Cross TA, Protein Sci. 2001 Nov;10(11):2241-50. PMID:11604531

Page seeded by OCA on Thu Jul 3 00:39:19 2008

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