8tnn

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'''Unreleased structure'''
 
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The entry 8tnn is ON HOLD until Paper Publication
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==Crystal structure of Epstein-Barr virus gH/gL/gp42 in complex with gp42 antibody A10==
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<StructureSection load='8tnn' size='340' side='right'caption='[[8tnn]], [[Resolution|resolution]] 3.36&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8tnn]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_gammaherpesvirus_4 Human gammaherpesvirus 4] and [https://en.wikipedia.org/wiki/Macaca_fascicularis Macaca fascicularis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8TNN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8TNN FirstGlance]. <br>
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Description:
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.36&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8tnn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8tnn OCA], [https://pdbe.org/8tnn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8tnn RCSB], [https://www.ebi.ac.uk/pdbsum/8tnn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8tnn ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/GH_EBVB9 GH_EBVB9] The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell. Membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL. Fusion of EBV with B-lymphocytes requires the additional receptor-binding protein gp42, which forms a complex with gH/gL. May also be required for virus attachment to epithelial cells.<ref>PMID:11021994</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Human gammaherpesvirus 4]]
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[[Category: Large Structures]]
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[[Category: Macaca fascicularis]]
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[[Category: Board N]]
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[[Category: Bu W]]
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[[Category: Cohen JI]]
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[[Category: Dowdell K]]
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[[Category: Hostal A]]
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[[Category: Kim J]]
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[[Category: Krogmann T]]
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[[Category: Kumar A]]
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[[Category: Lei Y]]
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[[Category: Marcotrigiano J]]
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[[Category: Pittaluga S]]
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[[Category: Wang Y]]
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[[Category: Zhang S]]

Revision as of 10:13, 27 March 2024

Crystal structure of Epstein-Barr virus gH/gL/gp42 in complex with gp42 antibody A10

PDB ID 8tnn

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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