8q69

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Current revision (13:06, 21 August 2024) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 8q69 is ON HOLD until Paper Publication
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==Crystal structure of HsRNMT complexed with inhibitor DDD1060606==
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<StructureSection load='8q69' size='340' side='right'caption='[[8q69]], [[Resolution|resolution]] 1.96&Aring;' scene=''>
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Authors: Petit, A.P., Fyfe, P.K.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8q69]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8Q69 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8Q69 FirstGlance]. <br>
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Description: Crystal structure of HsRNMT complexed with inhibitor DDD1060606
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.96&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8q69 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8q69 OCA], [https://pdbe.org/8q69 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8q69 RCSB], [https://www.ebi.ac.uk/pdbsum/8q69 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8q69 ProSAT]</span></td></tr>
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[[Category: Fyfe, P.K]]
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</table>
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[[Category: Petit, A.P]]
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== Function ==
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[https://www.uniprot.org/uniprot/MCES_HUMAN MCES_HUMAN] mRNA-capping methyltransferase that methylates the N7 position of the added guanosine to the 5'-cap structure of mRNAs. Binds RNA containing 5'-terminal GpppC.<ref>PMID:9790902</ref> <ref>PMID:9705270</ref> <ref>PMID:10347220</ref> <ref>PMID:22099306</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Fyfe PK]]
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[[Category: Petit AP]]

Current revision

Crystal structure of HsRNMT complexed with inhibitor DDD1060606

PDB ID 8q69

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