399d

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Current revision (09:26, 21 February 2024) (edit) (undo)
 
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=399d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=399d OCA], [https://pdbe.org/399d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=399d RCSB], [https://www.ebi.ac.uk/pdbsum/399d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=399d ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=399d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=399d OCA], [https://pdbe.org/399d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=399d RCSB], [https://www.ebi.ac.uk/pdbsum/399d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=399d ProSAT]</span></td></tr>
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== Publication Abstract from PubMed ==
 
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We have determined the structure of the dodecamer duplex d(CGCCCGCGGGCG)2. A careful use of the molecular replacement programme AMoRe has been essential in order to solve the structure. This dodecamer shows a unique conformation, quite different from all the previously studied oligonucleotide duplexes: the central octamer has an A conformation, but with a sharp 65 degrees kink in the centre; the terminal base-steps have a B-like conformation; the major groove is completely closed in the centre, a hollow molecule is thus found. The results obtained confirm the high degree of variability of DNA structure. A new type of kink and an intermediate A/B double-helical conformation have been found. Such intermediate conformation differs from those described in DNA polymerase complexes.
 
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Structure of the d(CGCCCGCGGGCG) dodecamer: a kinked A-DNA molecule showing some B-DNA features.,Malinina L, Fernandez LG, Huynh-Dinh T, Subirana JA J Mol Biol. 1999 Jan 29;285(4):1679-90. PMID:9917405<ref>PMID:9917405</ref>
 
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
 
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</div>
 
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<div class="pdbe-citations 399d" style="background-color:#fffaf0;"></div>
 
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== References ==
 
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<references/>
 
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Current revision

STRUCTURE OF D(CGCCCGCGGGCG)

PDB ID 399d

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