This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
8qam
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==vaccinia virus Uracil DNA glycosidase mutant I197K-V200E-L204K== | |
| - | + | <StructureSection load='8qam' size='340' side='right'caption='[[8qam]], [[Resolution|resolution]] 1.32Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8qam]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Vaccinia_virus_Copenhagen Vaccinia virus Copenhagen]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8QAM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8QAM FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.32Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8qam FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8qam OCA], [https://pdbe.org/8qam PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8qam RCSB], [https://www.ebi.ac.uk/pdbsum/8qam PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8qam ProSAT]</span></td></tr> |
| - | [[Category: Burmeister | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/UNG_VACCC UNG_VACCC] Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. Also part of a heterodimeric processivity factor which potentiates the DNA polymerase activity. Binds to DNA (By similarity). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Vaccinia virus Copenhagen]] | ||
| + | [[Category: Burmeister WP]] | ||
| + | [[Category: Tarbouriech N]] | ||
Current revision
vaccinia virus Uracil DNA glycosidase mutant I197K-V200E-L204K
| |||||||||||
