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1nci

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[[Image:1nci.gif|left|200px]]
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[[Image:1nci.png|left|200px]]
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==Overview==
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{{ABSTRACT_7885471}}
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Crystal structures of the amino-terminal domain of N-cadherin provide a picture at the atomic level of a specific adhesive contact between cells. A repeated set of dimer interfaces is common to the structure in three lattices. These interactions combine to form a linear zipper of molecules that mirrors the linear structure of the intracellular filaments with which cadherins associate. This cell-adhesion zipper may provide a mechanism to marshal individual molecular adhesive interactions into strong bonds between cells.
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==About this Structure==
==About this Structure==
1NCI is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NCI OCA].
1NCI is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NCI OCA].
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==Reference==
 
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Structural basis of cell-cell adhesion by cadherins., Shapiro L, Fannon AM, Kwong PD, Thompson A, Lehmann MS, Grubel G, Legrand JF, Als-Nielsen J, Colman DR, Hendrickson WA, Nature. 1995 Mar 23;374(6520):327-37. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7885471 7885471]
 
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: Thompson, A.]]
[[Category: Thompson, A.]]
[[Category: Cadherin]]
[[Category: Cadherin]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 02:22:09 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jun 26 17:45:17 2008''

Revision as of 14:45, 26 June 2008

Image:1nci.png

Template:STRUCTURE 1nci

STRUCTURAL BASIS OF CELL-CELL ADHESION BY CADHERINS


Template:ABSTRACT 7885471

About this Structure

1NCI is a Single protein structure of sequence from Mus musculus. Full crystallographic information is available from OCA.

Page seeded by OCA on Thu Jun 26 17:45:17 2008

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