6osn
From Proteopedia
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6osn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6osn OCA], [https://pdbe.org/6osn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6osn RCSB], [https://www.ebi.ac.uk/pdbsum/6osn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6osn ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6osn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6osn OCA], [https://pdbe.org/6osn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6osn RCSB], [https://www.ebi.ac.uk/pdbsum/6osn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6osn ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| - | == Disease == | ||
| - | [https://www.uniprot.org/uniprot/ROR2_HUMAN ROR2_HUMAN] Autosomal recessive Robinow syndrome;Brachydactyly type B. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. | ||
| - | == Function == | ||
| - | [https://www.uniprot.org/uniprot/ROR2_HUMAN ROR2_HUMAN] Tyrosine-protein kinase receptor which may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development. Phosphorylates YWHAB, leading to induction of osteogenesis and bone formation.<ref>PMID:17717073</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
Current revision
Potent and Selective Antitumor Antibody Targeting a Membrane-Proximal Epitope of ROR2
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