6vq2
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6vq2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6vq2 OCA], [https://pdbe.org/6vq2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6vq2 RCSB], [https://www.ebi.ac.uk/pdbsum/6vq2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6vq2 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6vq2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6vq2 OCA], [https://pdbe.org/6vq2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6vq2 RCSB], [https://www.ebi.ac.uk/pdbsum/6vq2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6vq2 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| - | == Disease == | ||
| - | [https://www.uniprot.org/uniprot/B2MG_HUMAN B2MG_HUMAN] Defects in B2M are the cause of hypercatabolic hypoproteinemia (HYCATHYP) [MIM:[https://omim.org/entry/241600 241600]. Affected individuals show marked reduction in serum concentrations of immunoglobulin and albumin, probably due to rapid degradation.<ref>PMID:16549777</ref> Note=Beta-2-microglobulin may adopt the fibrillar configuration of amyloid in certain pathologic states. The capacity to assemble into amyloid fibrils is concentration dependent. Persistently high beta(2)-microglobulin serum levels lead to amyloidosis in patients on long-term hemodialysis.<ref>PMID:3532124</ref> <ref>PMID:1336137</ref> <ref>PMID:7554280</ref> <ref>PMID:4586824</ref> <ref>PMID:8084451</ref> <ref>PMID:12119416</ref> <ref>PMID:12796775</ref> <ref>PMID:16901902</ref> <ref>PMID:16491088</ref> <ref>PMID:17646174</ref> <ref>PMID:18835253</ref> <ref>PMID:18395224</ref> <ref>PMID:19284997</ref> | ||
| - | == Function == | ||
| - | [https://www.uniprot.org/uniprot/B2MG_HUMAN B2MG_HUMAN] Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. | ||
==See Also== | ==See Also== | ||
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*[[MHC 3D structures|MHC 3D structures]] | *[[MHC 3D structures|MHC 3D structures]] | ||
*[[MHC I 3D structures|MHC I 3D structures]] | *[[MHC I 3D structures|MHC I 3D structures]] | ||
| - | == References == | ||
| - | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Current revision
HLA-B*27:05 presenting an HIV-1 14mer peptide
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Categories: Homo sapiens | Human immunodeficiency virus 1 | Large Structures | Appay V | Bell JI | Burgevin A | Fugger L | Gerstoft J | Hansjorg S | Harkiolaki M | Iversen AKN | Josephs TM | Kollnberger S | Ladell K | Mclaren JE | Price DA | Pymm P | Tenzer S | Van Endert P | Wee E | Weimershaus M
