Palbociclib

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<scene name='10/1001138/Overall/1'>The X-ray co-crystal structure of human CDK6 and Palbociclib</scene> ([[5l2i]]).
<scene name='10/1001138/Overall/1'>The X-ray co-crystal structure of human CDK6 and Palbociclib</scene> ([[5l2i]]).
 +
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<scene name='10/1001138/Binding_site/1'>Palbociclib binding site</scene>.
</StructureSection>
</StructureSection>
== References ==
== References ==
<references/>
<references/>

Revision as of 10:46, 11 October 2023

Caption for this structure

Drag the structure with the mouse to rotate

References

  1. Finn RS, Dering J, Conklin D, Kalous O, Cohen DJ, Desai AJ, Ginther C, Atefi M, Chen I, Fowst C, Los G, Slamon DJ. PD 0332991, a selective cyclin D kinase 4/6 inhibitor, preferentially inhibits proliferation of luminal estrogen receptor-positive human breast cancer cell lines in vitro. Breast Cancer Res. 2009;11(5):R77. PMID:19874578 doi:10.1186/bcr2419
  2. Rocca A, Farolfi A, Bravaccini S, Schirone A, Amadori D. Palbociclib (PD 0332991) : targeting the cell cycle machinery in breast cancer. Expert Opin Pharmacother. 2014 Feb;15(3):407-20. PMID:24369047 doi:10.1517/14656566.2014.870555

Proteopedia Page Contributors and Editors (what is this?)

Alexander Berchansky, Michal Harel

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