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8twe
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Cryo-EM structure of the PP2A:B55-FAM122A complex, B55 body== | |
| - | + | <StructureSection load='8twe' size='340' side='right'caption='[[8twe]], [[Resolution|resolution]] 2.55Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8twe]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8TWE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8TWE FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.55Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MLL:METHYL+L-LEUCINATE'>MLL</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8twe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8twe OCA], [https://pdbe.org/8twe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8twe RCSB], [https://www.ebi.ac.uk/pdbsum/8twe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8twe ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/2AAA_HUMAN 2AAA_HUMAN] The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. Required for proper chromosome segregation and for centromeric localization of SGOL1 in mitosis.<ref>PMID:16580887</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Fuller JR]] | ||
| + | [[Category: Padi SKR]] | ||
| + | [[Category: Page R]] | ||
| + | [[Category: Peti W]] | ||
Revision as of 13:16, 1 November 2023
Cryo-EM structure of the PP2A:B55-FAM122A complex, B55 body
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Categories: Homo sapiens | Large Structures | Fuller JR | Padi SKR | Page R | Peti W
