7jsl
From Proteopedia
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7jsl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7jsl OCA], [https://pdbe.org/7jsl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7jsl RCSB], [https://www.ebi.ac.uk/pdbsum/7jsl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7jsl ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7jsl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7jsl OCA], [https://pdbe.org/7jsl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7jsl RCSB], [https://www.ebi.ac.uk/pdbsum/7jsl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7jsl ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| - | == Disease == | ||
| - | [https://www.uniprot.org/uniprot/ERF_HUMAN ERF_HUMAN] Non-syndromic sagittal craniosynostosis;Crouzon syndrome. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry. | ||
| - | == Function == | ||
| - | [https://www.uniprot.org/uniprot/ERF_HUMAN ERF_HUMAN] Potent transcriptional repressor that binds to the H1 element of the Ets2 promoter. May regulate other genes involved in cellular proliferation. Required for extraembryonic ectoderm differentiation, ectoplacental cone cavity closure, and chorioallantoic attachment (By similarity). May be important for regulating trophoblast stem cell differentiation (By similarity). | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
Current revision
Crystal structure of the DNA binding domain of human transcription factor ERF in the oxidized form, in complex with double-stranded DNA ACCGGAAGTG
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