7lye

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Current revision (11:10, 23 October 2024) (edit) (undo)
 
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<StructureSection load='7lye' size='340' side='right'caption='[[7lye]], [[Resolution|resolution]] 1.76&Aring;' scene=''>
<StructureSection load='7lye' size='340' side='right'caption='[[7lye]], [[Resolution|resolution]] 1.76&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[7lye]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bothrops_moojeni Bothrops moojeni]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7LYE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7LYE FirstGlance]. <br>
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<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7LYE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7LYE FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.758&#8491;</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.758&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PE4:2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL'>PE4</scene>, <scene name='pdbligand=VRD:({3-[amino(oxo)acetyl]-1-benzyl-2-ethyl-1H-indol-4-yl}oxy)acetic+acid'>VRD</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PE4:2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL'>PE4</scene>, <scene name='pdbligand=VRD:({3-[amino(oxo)acetyl]-1-benzyl-2-ethyl-1H-indol-4-yl}oxy)acetic+acid'>VRD</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7lye FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7lye OCA], [https://pdbe.org/7lye PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7lye RCSB], [https://www.ebi.ac.uk/pdbsum/7lye PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7lye ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7lye FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7lye OCA], [https://pdbe.org/7lye PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7lye RCSB], [https://www.ebi.ac.uk/pdbsum/7lye PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7lye ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
 
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[https://www.uniprot.org/uniprot/PA2H1_BOTMO PA2H1_BOTMO] Snake venom phospholipase A2 homolog that displays local myotoxin and edema-inducing activities and is lethal by intraperitoneal injection.<ref>PMID:10620318</ref>
 
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bothrops moojeni]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Borges RJ]]
[[Category: Borges RJ]]
[[Category: Fontes MRM]]
[[Category: Fontes MRM]]
[[Category: Salvador GHM]]
[[Category: Salvador GHM]]

Current revision

Myotoxin I from Bothrops moojeni co-crystallized with synthetic inhibitor Varespladib (LY315920)

PDB ID 7lye

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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