8sgl

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Current revision (09:08, 4 June 2025) (edit) (undo)
 
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8sgl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8sgl OCA], [https://pdbe.org/8sgl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8sgl RCSB], [https://www.ebi.ac.uk/pdbsum/8sgl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8sgl ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8sgl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8sgl OCA], [https://pdbe.org/8sgl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8sgl RCSB], [https://www.ebi.ac.uk/pdbsum/8sgl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8sgl ProSAT]</span></td></tr>
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</table>
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== Disease ==
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[https://www.uniprot.org/uniprot/TCPE_HUMAN TCPE_HUMAN] Hereditary sensory and autonomic neuropathy with spastic paraplegia. The disease is caused by mutations affecting the gene represented in this entry.
== Function ==
== Function ==
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[https://www.uniprot.org/uniprot/TCPA_HUMAN TCPA_HUMAN] Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis (PubMed:25467444). The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance (PubMed:25467444). As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia (PubMed:20080638). The TRiC complex plays a role in the folding of actin and tubulin (Probable).<ref>PMID:20080638</ref> <ref>PMID:25467444</ref>
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[https://www.uniprot.org/uniprot/TCPE_HUMAN TCPE_HUMAN] Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin.<ref>PMID:20080638</ref>
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==See Also==
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*[[Transducin 3D structures|Transducin 3D structures]]
== References ==
== References ==
<references/>
<references/>

Current revision

CCT G beta 5 complex closed state 15

PDB ID 8sgl

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