1nq6

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{{STRUCTURE_1nq6| PDB=1nq6 | SCENE= }}
{{STRUCTURE_1nq6| PDB=1nq6 | SCENE= }}
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'''Crystal Structure of the catalytic domain of xylanase A from Streptomyces halstedii JM8'''
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===Crystal Structure of the catalytic domain of xylanase A from Streptomyces halstedii JM8===
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==Overview==
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Xylanases hydrolyze the beta-1,4-linked xylose backbone of xylans. They are of increasing interest in the paper and food industries for their pre-bleaching and bio-pulping applications. Such industries demand new xylanases to cover a wider range of cleavage specificity, activity and stability. The catalytic domain of xylanase Xys1 from Streptomyces halstedii JM8 was expressed, purified and crystallized and native data were collected to 1.78 A resolution with an R(merge) of 4.4%. The crystals belong to space group P2(1)2(1)2(1), with unit-cell parameters a = 34.05, b = 79.60, c = 87.80 A. The structure was solved by the molecular-replacement method using the structure of the homologue Xyl10A from Streptomyces lividans. In a similar manner to other members of its family, Xys1 folds to form a standard (beta/alpha)(8) barrel with the two catalytic functions, the acid/base and the nucleophile, at its C-terminal side. The overall structure is described and compared with those of related xylanases.
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(as it appears on PubMed at http://www.pubmed.gov), where 12876348 is the PubMed ID number.
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{{ABSTRACT_PUBMED_12876348}}
==About this Structure==
==About this Structure==
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[[Category: Xylan degradation]]
[[Category: Xylan degradation]]
[[Category: Xylanase]]
[[Category: Xylanase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 02:50:59 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 15:56:14 2008''

Revision as of 12:56, 27 July 2008

Image:1nq6.png

Template:STRUCTURE 1nq6

Crystal Structure of the catalytic domain of xylanase A from Streptomyces halstedii JM8

Template:ABSTRACT PUBMED 12876348

About this Structure

1NQ6 is a Single protein structure of sequence from Streptomyces halstedii. Full crystallographic information is available from OCA.

Reference

Structure of xylanase Xys1delta from Streptomyces halstedii., Canals A, Vega MC, Gomis-Ruth FX, Diaz M, Santamaria R RI, Coll M, Acta Crystallogr D Biol Crystallogr. 2003 Aug;59(Pt 8):1447-53. Epub 2003, Jul 23. PMID:12876348

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