1o0d
From Proteopedia
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{{STRUCTURE_1o0d| PDB=1o0d | SCENE= }} | {{STRUCTURE_1o0d| PDB=1o0d | SCENE= }} | ||
- | + | ===Human Thrombin complexed with a d-Phe-Pro-Arg-type Inhibitor and a C-terminal Hirudin derived exo-site inhibitor=== | |
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==Disease== | ==Disease== | ||
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[[Category: Ternary complex]] | [[Category: Ternary complex]] | ||
[[Category: Thrombin/active-site inhibitor/exo-site inhibitor]] | [[Category: Thrombin/active-site inhibitor/exo-site inhibitor]] | ||
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Revision as of 07:45, 28 July 2008
Contents |
Human Thrombin complexed with a d-Phe-Pro-Arg-type Inhibitor and a C-terminal Hirudin derived exo-site inhibitor
Template:ABSTRACT PUBMED 12781189
Disease
Known disease associated with this structure: Dysprothrombinemia OMIM:[176930], Hyperprothrombinemia OMIM:[176930], Hypoprothrombinemia OMIM:[176930]
About this Structure
1O0D is a Protein complex structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
D-Phe-Pro-Arg type thrombin inhibitors: unexpected selectivity by modification of the P1 moiety., Lange UE, Baucke D, Hornberger W, Mack H, Seitz W, Hoffken HW, Bioorg Med Chem Lett. 2003 Jun 16;13(12):2029-33. PMID:12781189
Page seeded by OCA on Mon Jul 28 10:45:50 2008